QUOTE(ATB @ Mar 7 2007, 04:20 PM) [snapback]391135[/snapback]
I would consider that niacin may become an essential for brain protection in aging, B6 probably isn't because most people do quite well out of the diet, and I've seen enough case reports to suggest that it may be moderately harmful within common supplement range to wonder if its worth the risk.
Folic acid joins the list. Vitamin K would seem to be especially for risk groups for osteoporosis and lots of people dont get enough on account on modern diets and food processing..
Magnesium - very common deficiency
Metabolic antioxidants - seem to be genuinely valuable i.e. co-q-10 and R-ALA
Zinc for some people, though it can accumulate in some people
Melatonin - many people may have damaged pineal glands or dysruption they can't avoid.
Chromium - for some people
Iodine - for some areas
For some people, the other B vits, Biotin, Pantothenic acid, riboflavin and thiamin, B12 all essential but there will be wide variations in the dietary supply.
Selenium - for some areas
Carnosine - seems to work for autism better than anything else, a dietary substance, usually ingested with heme iron - not everyone needs and can be harmed by.
Iron - women and children
Vitamin D3 - elderly, in-door workers, black people, winter. Diet no longer really supplies.
Lithium - for some people with specific concerns
DHEA - conditions can leave surpressed and it definitely can have beneficial effects
Milk Thystle - for liver conditions
Lutein, lycopene and alpha carotene and other antioxidants - for eyes, prostate and cardiovascular (probably) and other systems
Yes, good post. It is very refreshing to see a critical empirical look at supplements which are often over-hyped, usually by overly-enthusiastic/easy to convince consumers or, more often, the proprietor(s) themselves. Not that supplements and treatments which border the definition of "drug" aren't useful, but their utility depends almost entirely on the particular conditions of the receiving organism (i.e. the indvidual's human body).
(Warning, ranting will ensue below)
It is easy to get whipped up into a kind of group-think in which assumptions are not being questioned. If you've read the board for 3+ years (especially the Neuroscience/"Chemically Correct" section) I think you would notice, as I certainly do, a decline in skeptical, inquisitive discussion. I may be antiquarian, but I remember a time when someone would make a claim, and five minutes later others immediately call for evidence, and bring into critical discussion anything that was presented. Today it seems like posting an advertisement is enough to convince people, and maybe a few references that could be easily checked, but often aren't. It is the old adage, "if you aren't interested, don't read it." That's the definition of spam, it’s in a place that it shouldn't be, and where it shouldn't be represented. I'm sure a few people have received useful spam e-mails, but that doesn't make the concept of "spamming" any more legitimate. And I don't mean to disrespect any companies or anyone that markets/sells products, especially in an area where more research is needed and an increased degree of scientific attraction brought. But the presence and intimate involvement of the latter, I believe in scientific discussions, is more hindrance than help. This community has become so popular that I barely recognize it, but that is the reality. So as a gadfly, I urge a return to rigorous debate and analysis. This thread is a good start. I think that I've "articulated" what I've wanted to say for a while, which has in the past perhaps manifested itself in inappropriate ways. End rant.