I have selegiline made by apotex, 5mg tabs. started first dose today , 2.5mg with a fatty meal. will see how things go and post here.

took 2.5mg with food....then about 4 hours later on an empty stomach took 2g of DLPA, 45m-1h later I ate again and took another 2.5mg.
not sure how quick it kicked in, i feel pretty focused and a little wired...this is a late hour for me, im usually exhausted at this time and am in bed. although i did drink some green tea a couple hours ago, maybe there was some synergy there.

i would like to try NAC with this stuff but i just want to see what dep does first. not really sure whether to drop my SAMe or take that in the morning. someone suggested taking vitamin d which increases tyrosine hydroxylase, i already take about 2000iu per day along with some fish oil and i dont plan on stopping that.

day 2, took 5mg in the morning, provided a pretty good boost, however im thinking the timing of it may be of most importance. im already motivated enough at work, and im good at my job so i don't need any help in that department. however, my problem is getting home from work and having the desire to do anything productive (which is natural, i guess)...but i have schoolwork to do and other things that need attention. perhaps taking it when i get home from work is the best strategy....although it isn't like im not motivated right now having taken my morning dose.

i may continue with this for a week or so just to see what happens and if im not satisfied , i may take either a small dose of 2.5mg in the morning and 2.5 or 5mg at night, or 400mg SAMe in the morning and then 2.5-5mg dep at night.

Because it's a suicide inhbitor with a long half-life, I doubt the timing will have much effect with respect to MOA. The amphetamine metabolites, however, might be an issue with sleep if taken later in the day (total conjecture, I have no idea).

Have you looked into using it sublingually? My 1st deprenyl experiment, I used 2.5 mg sublingually which supposedly translates to 10 mg orally in terms of MAOI, but avoids the liver metabolism which produces the (purportedly helpful) amphetamine metabolites. Good if you get drug tested, good on $$, but you lose the amphetamines.

I slept a lot, more than normal, probably almost 10-11 hours. This may or may not be due to the deprenyl. Could be because I feel a bit of a cold coming on, time to pop some allibiotic CF by NOW.

Yes, I've looked into sublingual administration. Zelpar and Cyprenil are administered that way. Some say it works well, while others say there's an initial rush and then it subsides quicker than taking it with food.

Day 3, today I had off and didn't do any academic work either, so no real update here. Took 5mg with lunch and then around 6pm took 400mg of SAMe.

You have PEA right?

Nope.

The one long as log by Da_sense on this stuff is money. What he says is the truth on it.
You should expect afternoon naps after about a week of taking this.

I've read it extensively, in fact it's what got me to try it again. Is his experience similar to yours? Or do you mean just the naps?



I haven't quite noticed the nap factor, in fact, I've not had time for naps lately nor have I gotten tired in the middle of the afternoon as I usually do. I get a nice focus out of this stuff.

See, I don't think your taking enough IMHO.
I took 4-5mg ED for two months. And yes, I'm aware of the studies on mice longevity. Fuck mice

My experience was almost spot on with da_senses, but I think he mellowed it out abit to not scare anybody as to how much of a thinking focused machine you really become.
And yeah, afternoon naps are going to happen. The best stack ever is the Big T and deprynl, by the way

GH, that's what I'm taking....5mg ED.

In that case... I was taking the the type that starts with a J (Juprenil or something?). came in a little white cap bottle.
Anyway, good stuff.

Would I notice an appetite reduction on this stuff? Seems like I'm not as hungry the past 3 days or so around dinnertime, whereas normally , no matter how big of a lunch I had, I'd be starving.

I think Nandi has an article on bromo and weight loss somewhere (and I think Lyle McD has a book on it, too).

Something along the lines of appetite for high calorie foods being a result of the dopamine rush that ensues, and bromo's dopaminergic effects attenuating that response. Or something.

I would expect similar effects from anything that significantly increases dopamine or activates D2 receptors.

I don't knkow enough about the pharmacology, but I would "guess" that the appetite supression would be indirect; It's just part of the whole "in tune/focused" mentality you get with deprynl. Wastign food, pretty girls, dumb shit... All just a little less interesting on deprynl.

I'm really diggin this stuff, today was a really focused and productive day. I was in a great mood all day long .

Stellar, the funny thing is, for me atleast, when deprynl finally kicked in, I didn't spend much wasteful time on the internet. So I'll know it's working when you stop logging.
I really hope your wanting to become a machine off this stuff

The best thing you can do for yourself on Deprynl is, once a week, like a day you know is going to be long or a night your going to go out on the town, take a good sized dose of pea every 2 hours. Then don't do it again for a week.

I took 5mg today, as I have been every day. However, a couple hours later I took 2.5mg sublingually. It numbed my mouth which I don't take as a good sign and probably wont do this often....but within 10 minutes or so things really kicked in. Went on a walk and 30 minutes in, colors just seemed so vivid, almost like the first time I took liquid deprenyl.

I never noticed any improvement with sublingual administration, except for the numbness ofcourse. Tastes like shit too.