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D Sade
Ok...I need everyone's input here. I am doing my budget for the next 3 months, and just received final cost for NOxidant.

THis is the formula, for those that missed it:
Supplement Facts:
Serving Size: 3 Capsules
Servings Per Container: 30
Amount Per Serving % DV*

Gamma-Tocopherol 500 mg 50%
Selenium (.2%)
(yielding 200 mcg Selenium) 100 mg 0%
Alpha Lipoic Acid 100 mg 0%
Grape Seed Extract 200 mg 0%
Green Tea Extract (50%) 300 mg †
Quercetin 200 mg †
Apple Polyphenols (60%) 300 mg †
Zinc Aspartate (20%)
(standardized to 10mg zinc) 50 mg †
Copper Gluconate (20%)
(yielding 100mcg copper) 500 mcg †
Manganese Chelate - (20%)
(yielding .2mg Manganese) 1 mg †
Vitamin C 250 mg †

It is designed to quench free radicals (Reactive Nitrogen Species, mostly) and contains one of the most potent anti-oxidants known to man (Apple Polyphenols). Feedback on the product was stellar, but at the time it was too expensive to continue running.

This is a formula that I designed for Scivation a few years ago that they discontinued. What I need to know is:

Would you purchase this product at a $15.95 price tag?
nelix
That seems a large amount of unmixed Tocopherol's? Although everything I read about Gamma-Tocopherol is good.
I am worried about ALA polymerization, but if you are confident I am also.

The price seems very fair.
The Bionic Man
$15.95 seems like a very good price for an anti-oxidant complex...

that's about what I pay for my vitamin store-brand "super antioxidant", which is more of a multi-vitamin/antioxidant, and less that what I paid for my previous favorite (now discontinued) specialized anti-ox formula (DS Vigor)
Kimbo
I definitely would, assuming a 30 day supply.
Bachovas
Leaning towards a no.

The Zinc, Copper, Selenium and Manganese I can get from my multivitamin + creatine products + Zma (or similars). Sure they may not be in the same form, but still....

The ALA doesn't convince me in the mix, and what about the timing. Is it 1 serving at once or spread during the day?

Vit C? Nothing spectacularly attractive there.

Gamma-Tocopherol? D or DL form?

How about just packing in a bunch of stuff with super ORACs? And nothing else basically.
D Sade
QUOTE(Bachovas @ Jan 23 2008, 06:45 PM) [snapback]451152[/snapback]
Leaning towards a no.

The Zinc, Copper, Selenium and Manganese I can get from my multivitamin + creatine products + Zma (or similars). Sure they may not be in the same form, but still....

The ALA doesn't convince me in the mix, and what about the timing. Is it 1 serving at once or spread during the day?

Vit C? Nothing spectacularly attractive there.

Gamma-Tocopherol? D or DL form?

How about just packing in a bunch of stuff with super ORACs? And nothing else basically.

Zinc, Manganese, and copper are included as cofactors in the production of Superoxide Dismutase. The Gamma-Tocopherol is the natural form, and is particularly effective at dealing with Reactive Nitrogen Species.

The ingredient profile is put together to specifically combat RNS damage, but also Superoxide. We are looking deeper into this, as evidence is starting to point at the importance of a limited duration second messenger signal triggered by H2O2, in particular. Probably going to recommend taking the full serving before bed, rather than immediately after workout.

And just simply packing a bunch of High ORAC compounds, if I wanted to make a 1 dimensional product I would have. It holds no interest for me.
nelix
Don't get me wrong, I would buy it at that price if it only contained apple and grape seed at that price. I like it, I'm just asking questions.
SteveSliwa
QUOTE(D Sade @ Jan 23 2008, 02:44 PM) [snapback]451067[/snapback]
Ok...I need everyone's input here. I am doing my budget for the next 3 months, and just received final cost for NOxidant.

THis is the formula, for those that missed it:
Supplement Facts:
Serving Size: 3 Capsules
Servings Per Container: 30
Amount Per Serving % DV*

Gamma-Tocopherol 500 mg 50%
Selenium (.2%)
(yielding 200 mcg Selenium) 100 mg 0%
Alpha Lipoic Acid 100 mg 0%
Grape Seed Extract 200 mg 0%
Green Tea Extract (50%) 300 mg †
Quercetin 200 mg †
Apple Polyphenols (60%) 300 mg †
Zinc Aspartate (20%)
(standardized to 10mg zinc) 50 mg †
Copper Gluconate (20%)
(yielding 100mcg copper) 500 mcg †
Manganese Chelate - (20%)
(yielding .2mg Manganese) 1 mg †
Vitamin C 250 mg †

It is designed to quench free radicals (Reactive Nitrogen Species, mostly) and contains one of the most potent anti-oxidants known to man (Apple Polyphenols). Feedback on the product was stellar, but at the time it was too expensive to continue running.

This is a formula that I designed for Scivation a few years ago that they discontinued. What I need to know is:

Would you purchase this product at a $15.95 price tag?


Friendly thoughts.

What form of Vitamin C?
What type of selenium?
Green tea 50% for? EGCG?
D Sade
Vitamin C = ascorbic acid
Selenium = selenium yeast containing 2% selenium
GTE - correct, 98% Polyphenols, 70% Catechins, 50% EGCG.
CustomNW
Very interested in Apple Polyphenols
methodice
What is the deal with these apple polyphenols. Are they seen in any other product? Much research carried out on them?
SteveSliwa
QUOTE(methodice @ Jan 25 2008, 09:35 AM) [snapback]451639[/snapback]
What is the deal with these apple polyphenols. Are they seen in any other product? Much research carried out on them?


Nutrition. 2007 May;23(5):419-23.
Effects of Applephenon and ascorbic acid on physical fatigue.

Ataka S, Tanaka M, Nozaki S, Mizuma H, Mizuno K, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y. Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, Japan.

OBJECTIVE: We examined the effects of Applephenon and ascorbic acid administration on physical fatigue. METHODS: In a double-blinded, placebo-controlled, three-way crossover design, 18 healthy volunteers were randomized to oral Applephenon (1200 mg/d), ascorbic acid (1000 mg/d), or placebo for 8 d. The fatigue-inducing physical task consisted of workload trials on a bicycle ergometer at fixed workloads for 2 h on two occasions. During the test, subjects performed non-workload trials with maximum velocity for 10 s at 30 min (30-min trial) after the start of the test and 30 min before the end of the test (210-min trial). RESULTS: The change in maximum velocity between the 30- and 210-min trials was higher in the group given Applephenon than in the group given placebo; ascorbic acid had no effect. CONCLUSION: These results suggest that Applephenon attenuates physical fatigue, whereas ascorbic acid does not.
D Sade
I don't want to play my hand too soon, but Apple Polyphenols are probably one of the most exciting ingredients around.

We have this planned for 3-4 products already, including the DCP amplifier.

A quick Pubmed search will make QUITE a bit of sense to some of you.
rippedforce63
Hmmm inhibiting triglyceride absorption heh. cool.gif
D Sade
QUOTE(rippedforce63 @ Jan 25 2008, 02:46 PM) [snapback]451741[/snapback]
Hmmm inhibiting triglyceride absorption heh. cool.gif

Luckily we have a VERY strong source for these...but yeah, that is just one of the great things. smile.gif
D Sade
Order for raws is in.
etherdesign
Looks pretty good, and a hell of alot cheaper than the LEF Super Polyphenols Extracts I currently use.
D Sade
QUOTE (etherdesign @ Apr 13 2008, 07:08 PM) *
Looks pretty good, and a hell of alot cheaper than the LEF Super Polyphenols Extracts I currently use.

Thanks...it should be up for purchase this week (it is being shipped today...finally.)
lethaljd
And I just placed my big order Friday....Damn! Glad to see you followed this through to fruition. I've been waiting all year for this...
D Sade
QUOTE (lethaljd @ Apr 14 2008, 04:38 AM) *
And I just placed my big order Friday....Damn! Glad to see you followed this through to fruition. I've been waiting all year for this...

I have yet to draw a salary...everytime some funding comes in I get too excited for the new stuff, and I put the revenue back in...NOxidant was a huge priority for me, and I am excited to get it back in.

Mine will be here tomorrow!!
CustomNW
QUOTE (D Sade @ Apr 14 2008, 08:45 AM) *
I have yet to draw a salary...everytime some funding comes in I get too excited for the new stuff, and I put the revenue back in...NOxidant was a huge priority for me, and I am excited to get it back in.


Dito. Have a hard on for Apple Polyphenols.
D Sade
QUOTE (CustomNW @ Apr 14 2008, 05:36 AM) *
Dito. Have a hard on for Apple Polyphenols.

That's HardCore!!

/Get it? Like Apple Cores...HAHAHAHAHAHAH...ok, I'll shut up.
CustomNW
QUOTE (D Sade @ Apr 14 2008, 09:39 AM) *
That's HardCore!!

/Get it? Like Apple Cores...HAHAHAHAHAHAH...ok, I'll shut up.


THIS is hardcore....Use NOxidant to cleanse this image out of your mind smile.gif
D Sade
Always whipping out the Hoff...

/I think eye bleach will be needed here.
babyblu
Click to view attachment

Nice, Hoff-time it is!!!

bb
D Sade
QUOTE (babyblu @ Apr 14 2008, 06:15 AM) *
Click to view attachment

Nice, Hoff-time it is!!!

bb

He's got it wrong...that's not doggystyle.
babyblu
No silly DSade, Hoff is breast feeding. See it is a well known fact (in Germany of course) that Hoff's breast milk contains amazing dosages of GH, SARMS, and other various misc. anabolics/androgens. That is the source of his manly man-ness. After the puppy got done breastfeeding it turned into this:

Click to view attachment
Kimbo
KIT: Michael, you're inside me *moan*
babyblu
Deeeep inside I'm sure.

bb
lethaljd
bump for update on ETA @ retailer?
D Sade
QUOTE (lethaljd @ Apr 19 2008, 10:41 AM) *
bump for update on ETA @ retailer?

http://customnutritionwarehouse.com/noxida...aps-p-1504.html

First one up...talk about quick!!
lethaljd
QUOTE (D Sade @ Apr 19 2008, 02:49 PM) *


That label looks as rad as the price point. Killer re-intro DSade!
D Sade
QUOTE (lethaljd @ Apr 20 2008, 06:28 AM) *
That label looks as rad as the price point. Killer re-intro DSade!

Thank you, my friend...this took some big time negotiations to get raws down to hit the target price...I am so glad to see this out again - I feel fantastic.
Steveo
Also now in stock at Nutraplanet smile.gif
http://www.nutraplanet.com/product/rpn/nox...0-capsules.html

Nice to see NOxidant again dsade.
ersatz
Decent product, but we want something with an absurd ORAC of 23,725,496 that means fuck all. Should be fairly effective at combating ROS though I think better alternatives exist though they would push the price point quite a bit higher. Do you plan on releasing similar products to combat AGE or upregulate SIRTUIN-1?
D Sade
QUOTE (ersatz @ Apr 21 2008, 08:34 PM) *
Decent product, but we want something with an absurd ORAC of 23,725,496 that means fuck all. Should be fairly effective at combating ROS though I think better alternatives exist though they would push the price point quite a bit higher. Do you plan on releasing similar products to combat AGE or upregulate SIRTUIN-1?

Not until we can do it right. My research time has taken a huge hit lately, with supplier problems...and without revenue then further products will never happen.

Gotta move 2 steps forward, then wait until resources accrue to move ahead again.
ScottL
D Sade,

Good product, though the only thing I'm not already getting is the apple polyphenols. Any chance I could buy some off you? I know caps is too much to hope for, so I'd gladly take bulk.

Thanks.
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