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Lost Metal
I just want to spread some Febuary awareness and
remind everyone of something very simple.

Be careful what supplement companies you buy from!

We spend so much time researching supplements,
don't overlook researching brands too.

There has been some rumours floating around a
couple various forums I visit, you've all probably seen
a hint about it too.

That some of the new emerging and fastly rising supplement
companies are actually based out of home garages and
living rooms. These are not the type of environments
that insure quality.

If your going to put something into your body to help
you gain muscle or lose fat, you don't want it to be
contaminated, dirty, or mislabeled entirely, right?

Some of my favorite and highly trusted brands are,
Avant Labs
Ergopharm
Primaforce
Giant Nutrition
Designer Supplements
Avant Research
Dopamine
QUOTE(Lost Metal @ Feb 4 2008, 03:12 PM) [snapback]454487[/snapback]
I just want to spread some Febuary awareness and
remind everyone of something very simple.

Be careful what supplement companies you buy from!

We spend so much time researching supplements,
don't overlook researching brands too.

There has been some rumours floating around a
couple various forums I visit, you've all probably seen
a hint about it too.

That some of the new emerging and fastly rising supplement
companies are actually based out of home garages and
living rooms. These are not the type of environments
that insure quality.

If your going to put something into your body to help
you gain muscle or lose fat, you don't want it to be
contaminated, dirty, or mislabeled entirely, right?


I agree entirely with the thrust of your post, and it brings to mind the proverbial judgment that one must "trust, but verify." In many cases offense is taken when documentation or other types of evidence is requested as implying some kind of malicious or insulting behavior on the part of the consumer. A greater degree of transparency would enhance the "buying experience" of the average supplement consumer by ensuring product safety, while at the same time maintaining a high standard of evidence in product efficacy on the market.

Are their any recent revelations that you've come across concerning the issues you addressed here?
nelix
I'll add Now Foods, RPN (I am pretty sure there soap is made in dsade's yard... but damn it's good) and Scivation (I know, Primaforce... But still).

I know we can't really list the bad ones, but if you have such a list, I'd love you to PM it to me.
SupremeSportsEnhancements
The recent BSN lawsuit shocked me. Big companies like BSN and IBE demonstrate that ANY COMPANY, no matter how big or innovative they are, is NEVER exempt from srcutiny.

The industry is very STALE right now in my opinion; a complete and total lack of innovation, with the exception of a few good companies. Everyone releases the SAME OLD GARBAGE, or when one company DOES create something unique and effective, every other company tries to cash-in.

Ultimately, I think it starts at the TOP. You can't manufacture bodybuilding supplements if you don't understand nutraceuticals AND BODYBUILDING NUTRITION. You can have a BA or a MASTERS in Chemistry, but if you LACK KNOWLEDGE OF BODYBUILDING NUTRITION, you are ill-equipped to design and develop bodybuilding supplements.

In conculsion, not all companies are INNOVATIVE, but they may be TRUSTWORTHY, which is equally as important. Any reputable company will be able to provide COA's for their products, and contract agreements for patented ingredients. Furthermore, if a company does not have a TAX ID, it is NOT a company.

My name is Ross, I am the Owner & President of Supreme Sports Enhancements, a nutraceutical supplement company located in Jersey City, NJ.

Supreme Sports Enhancements is NOT your average supplement company with your average product line. We specialize in the conception and formulation of highly unique and effective bodybuilding products that are SCIENTIFICALLY PROVEN to work.

If you are tired of wasting your hard-earned money on the same old ineffective garbage, have no fear....SSE is here! I look forward to getting to know all of you here ar M&M!


-Ross
Owner & President of Supreme Sports Enhancements
Dopamine
QUOTE(SupremeSportsEnhancements @ Feb 4 2008, 04:12 PM) [snapback]454504[/snapback]
The recent BSN lawsuit shocked me. Big companies like BSN and IBE demonstrate that ANY COMPANY, no matter how big or innovative they are, is NEVER exempt from srcutiny.


For those interested: a link to the complaint (PDF).
babyblu
But I would like to say that I have reviewed the standards for several different states on manufacturing of cosmetics (which most states classify supplements as), and the standards are not excruciatingly high or demanding. So while you may find it perturbing that some supp companies produce products in their home, it is more than likely 100% legal and acceptable under state law.

Of course a lot of people in the bb community dont want additional regulation of the industry. After all regulation led to the demise of the first generation of prohormones.

bb
SupremeSportsEnhancements
QUOTE(babyblu @ Feb 4 2008, 06:17 PM) [snapback]454520[/snapback]
But I would like to say that I have reviewed the standards for several different states on manufacturing of cosmetics (which most states classify supplements as), and the standards are not excruciatingly high or demanding. So while you may find it perturbing that some supp companies produce products in their home, it is more than likely 100% legal and acceptable under state law.

Of course a lot of people in the bb community dont want additional regulation of the industry. After all regulation led to the demise of the first generation of prohormones.

bb

I have NEVER heard of a supplement company manufacturing products in a HOME. Who does this? That's crazy...Is that compliant with GMP & NSF standards?
Rodzilla
QUOTE(SupremeSportsEnhancements @ Feb 4 2008, 06:26 PM) [snapback]454522[/snapback]
I have NEVER heard of a supplement company manufacturing products in a HOME. Who does this? That's crazy...Is that compliant with GMP & NSF standards?

where is your factory? tongue.gif
SupremeSportsEnhancements
QUOTE(Rodzilla @ Feb 4 2008, 06:34 PM) [snapback]454526[/snapback]
where is your factory? tongue.gif


Supreme Sports Enhancements
629 Grove St.
Jersey City, NJ 07310
1800-777-0901


My contract manufacturer is NC World Wide

Where is yours? rolleyes.gif
lethaljd
bump for NOW Foods. I'd also place Labrada and Optimum Nutrition in my "trusted" list.

That PDF of the lawsuit is a damn interesting read. Scumbags. If it sounds too good to be true, it probably is.
Rodzilla
QUOTE(SupremeSportsEnhancements @ Feb 4 2008, 06:41 PM) [snapback]454527[/snapback]
Supreme Sports Enhancements
629 Grove St.
Jersey City, NJ 07310
1800-777-0901


My contract manufacturer is NC World Wide

Where is yours? rolleyes.gif

Damn, I've been meaning to check your website out, I will in about 5 mins here.

Our's is in T Savage's living room/kitchen, and bathroom tub. laugh.gif
FunkMasterFlex


Yeah...Im about to start my own supp company.... rolleyes.gif
babyblu
Some products fall in as cosmetics. Remember most people only have to meet state standards. Look over your state's laws regarding prodution of cosmetics.

bb
Odium
Amazing how so many of those Supplement Direct products are verified.

Anyone else notice that the mailing addresses for supplementdirect.com and supplementpolice.com are the same?

Shady shit.
SupremeSportsEnhancements
QUOTE(babyblu @ Feb 4 2008, 09:26 PM) [snapback]454561[/snapback]
Some products fall in as cosmetics. Remember most people only have to meet state standards. Look over your state's laws regarding prodution of cosmetics.

bb


Anything consumed orally or ingested is NOT a cosmetic product. A transdermal solution may be considered a "cosmetic product", but nothing that is meant for human consumption.

If a company is not willing to invest in enough inventory that would warrant a contract manufacturer, it should not develop the product. Starting a business requires an initial investment. Manufacturing your own supplements in your own home is just not acceptable, don't you agree?
Dopamine
QUOTE(SupremeSportsEnhancements @ Feb 4 2008, 04:12 PM) [snapback]454504[/snapback]
Ultimately, I think it starts at the TOP. You can't manufacture bodybuilding supplements if you don't understand nutraceuticals AND BODYBUILDING NUTRITION. You can have a BA or a MASTERS in Chemistry, but if you LACK KNOWLEDGE OF BODYBUILDING NUTRITION, you are ill-equipped to design and develop bodybuilding supplements.


I agree. Most supplement company owners are business administration majors looking to turn a profit without detailed consideration that adds to the overall cost (e.g. 3rd party testing) and undermines the bottom line. Such circumstances are entirely understandable and plausible, hopefully leading the consumer to a more informed decision regarding the quality and presence or absence of the listed ingredients.

QUOTE(SupremeSportsEnhancements @ Feb 4 2008, 04:12 PM) [snapback]454504[/snapback]
Any reputable company will be able to provide COA's for their products


I think we can all agree on that - especially companies with few employees and limited operations. Such limited resources can ultimately lead to financial realities that render independent laboratory assays cost prohibitive.

I'm glad you emphasize very forthrightly the need for quality and independent verification in a market that is most likely infested with fraudulently mislabeled supplements.
SupremeSportsEnhancements
QUOTE(Dopamine @ Feb 4 2008, 10:16 PM) [snapback]454585[/snapback]
I agree. Most supplement company owners are business administration majors looking to turn a profit without detailed consideration that adds to the overall cost (e.g. 3rd party testing) and undermines the bottom line. Such circumstances are entirely understandable and plausible, hopefully leading the consumer to a more informed decision regarding the quality and presence or absence of the listed ingredients.
I think we can all agree on that - especially companies with few employees and limited operations. Such limited resources can ultimately lead to financial realities that render independent laboratory assays cost prohibitive.

I'm glad you emphasize very forthrightly the need for quality and independent verification in a market that is most likely infested with fraudulently mislabeled supplements.


Indeed, most companies would rather make a PROFITABLE product than an EFFECTIVE product. Take several popular ingredients for example, all of which are in our product AndroGenerator:

Tribulus Terrestris

Tribulus is probably the most popular anabolic herb. Unfortunately, it has also been the victim of Supplement Industry DECEIT. You see, Tribulus Terrestris PLANT is almost USELESS. It only contains a trace amount of the ACTIVE CHEMICAL responsible for increasing LH/Testosterone, a Frustanol Saponin called Protodioscin. It is PROTODIOSCIN that matters, and PROTODIOSCIN ONLY! But this is where things get even TRICKIER...

A Tribulus 20% extract costs 5 times as much as Tribulus PLANT!

Tribulus contains MANY Frustanol Saponins. BUT, the ONY Frustanol Saponin that matters is PROTODIOSCIN. many supplement companies will sell a Tribulus product containing 40% Frustanol Saponins, but it only has 2% Protodioscin or LESS! Make sure your Tribulus product is STANDRADIZED extract containing 10% Protodioscin or HIGHER. AndroGenerator contains 20% PROTODIOSCIN!


Eurycoma Longifolia

Eurycoma Longifolia has been used for centuries by the Asian population. Touted for it's ability to increase PENIS SIZE, the Malaysian government began to closely resarch the herb. In their studies, they discovered that Eurycoma increased testosterone levels and then IDENTIFIED the active chemicals responsible for the documented effects. These "Eurypeptides and Glycosapins" have been CLINICALLY PROVEN to not only increase total and free TESTOSTERONE, to also also incerase HGH & IGF-1, while simultaneously decreasing cortisol and increasing cAMP.

LJ100 is the ONLY STANDARDIZED Eurycoma Longifolia extract in the WORLD, containing 22% bioactive Eurypeptides. Products containing "Tongkat Ali" or "Long Jack" are NOT to be confused with the ONLY STANDARDIZED Eurycoma extract in the WORLD. AndroGenerator contains 200mgs of LJ100 per serving!

"Long Jack" and "Tongkat" are CHEAP and ineffective. LJ100 costs THOUSANDS OF DOLLARS PER KILO.


Vitex Agnus Castus

Vitex is an incredible herb that not only increases TESTOSTERONE, it also decreases ESTROGEN AND PROLACTIN! There is no other herb that will totally enhance the male hormonal profile like Vitex. Vitex is an important inclusion to an herbal testosterone booster, as it will not only help to further enhance testosterone production, it will also maintain healthy levels of estrogen and prolactin.

Make sure that any supplement containing Vitex is standardized for at least .5% avenoscides, and is dosed at 150-200mgs per serving. Many companies underdose or use inferior quality extracts. Do not be fooled! AndroGenerator contains 200mgs of Vitex per serving.
babyblu
Oh no Ross I'm not disagreeing with you. Im simply stating facts.

bb
Benson
QUOTE(SupremeSportsEnhancements @ Feb 4 2008, 09:29 PM) [snapback]454589[/snapback]
It only contains a trace amount of the ACTIVE CHEMICAL responsible for increasing LH/Testosterone, a Frustanol Saponin called Protodioscin. It is PROTODIOSCIN that matters, and PROTODIOSCIN ONLY!


Is there any data to support this? Aside from some of the original corporate research that showed that a fairly unsophisticated extract of trib increased LH, I was not aware that there had been any studies in animals or humans to support the use of trib as a LH releaser/mimetic...
SupremeSportsEnhancements
QUOTE(Benson @ Feb 5 2008, 11:18 AM) [snapback]454688[/snapback]
Is there any data to support this? Aside from some of the original corporate research that showed that a fairly unsophisticated extract of trib increased LH, I was not aware that there had been any studies in animals or humans to support the use of trib as a LH releaser/mimetic...


This study demonstrates that a 10% Protodioscin extract increases TESTOSTERONE:

TRIBESTAN EFFECT ON THE CONCENTRATION OF SOME HORMONES IN THE SERUM OF HEALTHY SUBJECTS

S. Milanov, A. Maleeva, M. Taskov

RIRR - Radioisotope and Radioimmunological Laboratory, Sofia

Chemical Pharmaceutical Research Institute,
Sofia, Bulgaria

SUMMARY

Tribestan effect has been studied on the serum concentration of hypophyseal hormones, of ACTH, STH, LH, FSH, adrenal hormone aldosterone and cortisol and sex hormones - testosterone and estradiol. The experiments have been carried out on 8 males and 8 females, aged 28 - 45 years of age. The product was perorally administered in a single dose of 250 mg, three times daily for 5 days. Serum samples were withdrawn at 8 a.m. and 12 a.m., prior to and post treatment. The product has been established not to change essentially the concentrations of adrenal hormones and of ACTH. The hypophyseal-gonadal axis however has significantly been affected in the females with predominantly increased concentration of FSH and estradiol and in the males - mainly of LH and the testosterone. The mechanism of that action is presumed to be complicated and realized both by direct effect on gonadal apparatus and by the tropic hormones.
The probable established changes in the concentration of the hormones studied do not get out of the frames of the physiological limits.

The lyophilized extract of Tribulus terrestris, introduced in veterinary practice as TB-68, has pronounced sex-stimulating function. The initial studies of this product showed that it stimulates the spermatogenesis of albino rats (Vankov S., et al., 1973) and enhanced the ovulation of female rats (Vankov S. et al. 1973). Zarkova S. (1976) has also established in rats an increased number of spermatogonia, spermatocytes as well as increase of neutral mucopolysaccharides in seminiferous tubules of the testes. Gendzhev Z. and S. Zarkova, in other experiments (1978) proved the increase of spermatic reserve in the epididymis of rats.

With the view to the need of human medicine of a product stimulating sexual function, Tribestan was formulated on the base of the indicated phytochemical product. It contains saponins of furostanol type (Tomova M. et al., 1978). The first studies of Tribestan confirmed its high sex-stimulating activity in experimental animals (Zarkova S., 1981). Later, the clinical studies established a similar stimulating effect in humans as well (Protich M. at al. 1981). The present study was carried out with a view to throwing light on some aspects of the mechanism of that action of Tribestan, aiming at attaining an effect from the product on the serum concentration of some hypophyseal, sexual and adrenal hormones.

MATERIALS AND METHODS

The experiments were performed on 16 subjects (8 females and 8 males), aged 28-45. All subjects were in good health, without any complaints and good capacity for work. The following schedule was used:
1. The basic levels of hypophysiotropic hormones (ACTH, STH, LH, FSH), of sexual hormones (testosterone and estradiol) and of adrenal hormones (aldosterone and cortisol) were determined. They were determined twice, at 8 a.m. and 12 p.m. - one day prior to Tribestan treatment.
2. The treatment with the product was initiated on the following day, which was periodically administered, 250 mg, three times daily for 5 days.
3. After the termination of Tribestan treatment (day sixth after the initiation of the experiment), blood was again withdrawn (at the same hour - 8:00 a.m. and 12 p.m.) for the determination of the concentration of the indicated hormones.

The work proceeded in the following way: after centrifugation of 6 - 8 ml blood, the serum obtained was frozen at 20°C till the day of the determination of hormonal concentration. The determination was performed by radioimmune tests. LH and FSH were determined by the modified method of Midgley A.R., (1967), making use of some kits of Biodata company, Italy and ACTH and STH - according to the method of Berson S.A. and R. S. Yalow (1963). Testosterone was evaluated by the method of William R. H. (1968), and of estradiol by Orezyk G.P. et al. (1974), making use of kits of Sorin Company, Belgium for both hormones. The adrenal hormones cortisol and aldosterone were also determined by kits of that company, making use of Vescei P. (1974) and of William G and R. Hunderwood (1974).

The obtained results were statistically processed by variation analysis, by Student - t test.

RESULTS AND DISCUSSION

As could be seen from Table 1, LH level in the males was elevated with a high significance after the treatment (p < 0.001). The changes affected both samples to the same rate (at 8 a.m. and 12 p.m.). FSH concentration was not affected under the same conditions. The other two hypophyseal hormones, ACTH and STH were not changed.

An insignificant tendency to elevation was observed in STH level (mean values - 2.9 prior to and 3.2 mg/ml post treatment) in some of the cases. The level of sex hormones was strongly affected. Thus testosterone concentration was three-fold (2) increased and that of estradiol - about 1.5 times (Table 1).

Table 1
Hormone Prior to Tribestan
Post Tribestan

8 a.m.
12 p.m.
8 a.m.
12 p.m.

LH, mIU/ml X 13.0 14.38(1) 37.25 24.75
SX 0.64 0.73 1.01 0.79
Pt 0.001 0.001
FSH, mIU/ml X 13.38 13.50 13.38 11.38
SX 0.35 0.28 0.35 0.36
Pt >0.5 >0.5
Testosterone, ng % X 628 610 882 845
SX 48 46 35 32
Pt <0.001 <0.001
Estradiol pg/ml X 79 76 133 137.5
SX 3.46 2.24 6.72 5.86
Pt <0.001 <0.001

LH concentration was also increased in females under Tribestan effect. What impressed was that the significance was lower than the first sample. The greatest discrepancy, as compared with the results of the males, was the sharp stimulation of FSH. A strong effect was observed there, which could be explained by blood withdrawal during the early phase of the menstrual cycle, the so-called follicular phase. Estradiol was also strongly affected (Pt < 0.001), whereas testosterone in the females during the early hours of the day was less affected (Table 2).

Table 2
Hormone
Prior to Tribestan
Post Tribestan

8 a.m.
12 p.m.
8 a.m.
12 p.m.

LH, mIU/ml X 15.25 13.50 17.13 16.88
SX 0.64 0.87 0.73 0.35
Pt 0.02 0.001
FSH, mIU/ml X 11.00 11.88 17.75 15.25
SX 0.13 0.09 0.71 0.38
Pt 0.001 0.001
Estradiol mIU/ml X 72.13 59.38 77.13 87.50
SX 6.02 5.73 5.47 3.24
Pt 0.5 0.001

The level of adrenal hormone was identically affected both in males and females (Table 3). A significant increase of the concentration was also established though that effect had a relatively low significance (p < 0.05). At the same time, cortisol level was no changed (Table 3).



Table 3
Aldosterone Cortisol
Prior to Post Prior to Post
X 11.59 13.77 8.63 8.63
S 2.52 3.48 2.20 1.92
SX 0.63 0.87 0.55 0.48
Pt 0.05 0.05

The results obtained provided grounds to admit that Tribestan had a pronounced stimulating effect on the secretion of some hormones. The effect on the hormones along the hypophyseal-gonadal axis was particularly well manifested. The effect was manifested both at hypophyseal and gonadal level. Some sexual discrepancies were also established. Thus, FSH was mainly affected in the females. The presence of that hormone is exceptionally important during the follicular phase for the development of the follicle. When its development is stimulated, its secretory ability is also intensified and hence - estradiol level is elevated. Lutenizing hormone is more strongly influenced in the male, which on its part stimulates the secretion of testosterone.

ACTH and cortisol were not changed suggesting that they were not significantly involved in the realization of Tribestan effects. The tendency of stimulation of STH and aldosterone explained the activation of the anabolic processes in the body and general stimulating action of the product. The absence of effect on the level of cortisol showed however that the general tonic action was very strongly manifested.

It should be stressed that the level of the hormones studied did not go out beyond the physiological frames i.e. it did not disturb the physiological mechanisms of hormonal regulation.

References

Vankov S., S. Zarkova, Z. Gendzhev, M. Tomova - Effect of TB-68 on the spermatogenesis in albino rats. Proceeding of the Third National Conference of Pharmacology and Clinics of New Bulgarian Drugs, Sofia, November 14-16, 1973, v.2, 161-163.
Vankov S., S. Zarkova, M. Tomova - TB-68 effect on ovulation of albino rats. Proceedings of Third National Conference of Pharmacology and Clinics of New Bulgarian Drugs, Sofia, November 14-16, 1973, v.2, 165-167.
Gendzhev Z., S. Zarkova - Effect of the phyto-pharmaceutical TB-68 on the number of spermatozoa in epididymis of rat. Med. Archive, 1978, N I, 113-118.
Dimova P., M. Taskov - Comparative enzyme-histological studies of some phyto-products. MBI (at the printer's), 1981.
Zarkova S. - Morphological and histological changes in testes of rat under the effect of TB-68, Med. Archive, 1976, N 4, 49-53.
Protich M., D. Zvetanov, V. Nalbanski, R.Stanislavov, M.Kazarova - Clinical trial of Tribestan on infertile males, MBI (at the printer's).
Tomova M., V. Gyulemetova, S. Zarkova - Author's certificate N 77584 A 61 K 35/1978.
Berson S.A., R. S. Yalow - Immunoassay of protein hormones, The Hormones, Vol. V, Acad. Press., New York, 1963.
Midgley A.R. - Radioimmunoassay for Human, J. Clin. Endocr., 1967, 27, 295.
Orezyk, Gaylo P., Burton v. Caldwell, Harold H. Behrmaan - Methods of Hormone Radioimmunoassay - Ed. B. Jaffe, H. Berhmaan, A6. Press, NJ, London, 1974, 333-343.
Vescei P. - Glicocorticoids: Cortisol Corticosterone - Methods of Hormone Radioimmunoassay; Ed. B. Jaffe and H. Behrmaan, Ac. Press, NJ, London 393-412.
William R.H. - Textbook of Endocrinology 4th Edit. Saunder, Philadelphia, 1968.
Williams Gordon H., Richard H. Hunderwood - Methods of Hormon Radioimmunoassay; Ed. B. Jaffe and H. Behrmaan, Ac. Press, NJ, London, 1974, 371-390.

--------------------------------------------------------------------------------
SupremeSportsEnhancements
This study demonstrates that Protodioscin is the active steroidal saponin:

The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction - an evaluation using primates, rabbit and rat.Gauthaman K, Ganesan AP.
Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, 119074 Singapore.

Hormonal effects of Tribulus terrestris (TT) were evaluated in primates, rabbit and rat to identify its usefulness in the management of erectile dysfunction (ED). TT extract was administered intravenously, as a bolus dose of 7.5, 15 and 30mg/kg, in primates for acute study. Rabbits and normal rats were treated with 2.5, 5 and 10mg/kg of TT extract orally for 8 weeks, for chronic study. In addition, castrated rats were treated either with testosterone cypionate (10mg/kg, subcutaneously; biweekly for 8 weeks) or TT orally (5mg/kg daily for 8 weeks). Blood samples were analyzed for testosterone (T), dihydrotestosterone (DHT) and dehydroepiandrosterone sulphate (DHEAS) levels using radioimmunoassay. In primates, the increases in T (52%), DHT (31%) and DHEAS (29%) at 7.5mg/kg were statistically significant. In rabbits, both T and DHT were increased compared to control, however, only the increases in DHT (by 30% and 32% at 5 and 10mg/kg) were statistically significant. In castrated rats, increases in T levels by 51% and 25% were observed with T and TT extract respectively that were statistically significant. TT increases some of the sex hormones, possibly due to the presence of protodioscin in the extract. TT may be useful in mild to moderate cases of ED.

PMID: 18068966 [PubMed - in process]

Benson

Cool. Thanks. The first one is the original corporate research that started all this I think but I was not aware of the second study...I find the rise in DHEAS particularly interesting...makes me wonder if stimulation of DHEA production is the actual MOA rather than Leydig cell stimulation...IOW, the increase in T is a result of a rise in adrenal not gonadal sex steroids. I also wonder why studies of Trib in humans has resulted in no change in sex steroid levels or body comp...
1fast400
BSN=100m+ company with playboy models as receptionist
IBE= very very small compared to BSN and likely makes things in a bathtub.

Please don't ever think they are anywhere near the same.
SupremeSportsEnhancements
QUOTE(1fast400 @ Feb 5 2008, 10:07 PM) [snapback]454860[/snapback]
BSN=100m+ company with playboy models as receptionist
IBE= very very small compared to BSN and likely makes things in a bathtub.

Please don't ever think they are anywhere near the same.


LOL, good point. I was simply stating that IBE was INNOVATIVE to bring Epithio to the market. I know they aren't a large company.
D Sade
QUOTE(SupremeSportsEnhancements @ Feb 5 2008, 07:10 PM) [snapback]454862[/snapback]
LOL, good point. I was simply stating that IBE was INNOVATIVE to bring Epithio to the market. I know they aren't a large company.

IBE didn't....I did.
SupremeSportsEnhancements
QUOTE(D Sade @ Feb 5 2008, 10:23 PM) [snapback]454868[/snapback]
IBE didn't....I did.


You are the creator of "Havoc"? If so, my hat is off to you! Remarkable compound indeed!
D Sade
QUOTE(SupremeSportsEnhancements @ Feb 5 2008, 07:25 PM) [snapback]454869[/snapback]
You are the creator of "Havoc"? If so, my hat is off to you! Remarkable compound indeed!

Yep..my company brought the first Epithio compound to the market.

We were just glad to be able to offer a hormonal product that is both VERY effective, and relatively benign.
SupremeSportsEnhancements
QUOTE(D Sade @ Feb 5 2008, 10:28 PM) [snapback]454873[/snapback]
Yep..my company brought the first Epithio compound to the market.

We were just glad to be able to offer a hormonal product that is both VERY effective, and relatively benign.


Much respect for doing so.

Maybe I will see you at the Arnold. smile.gif
D Sade
We'll be there...just not with a booth. I have some meetings scheduled, and I love catching up with a few people I never get to see anywhere else.
Lost Metal
Is there any scientific research behind the actives in Vitex, increasing test and lowering estros?
SupremeSportsEnhancements
QUOTE(Lost Metal @ Feb 6 2008, 12:38 PM) [snapback]455072[/snapback]
Is there any scientific research behind the actives in Vitex, increasing test and lowering estros?


Vitex increases LH and lowers estrogen and prolactin:

English Title: Evidence for estrogen receptor β-selective activity of Vitex agnus-castus and isolated flavones.

Personal Authors: Jarry, H., Spengler, B., Porzel, A., Schmidt, J., Wuttke, W., Christoffel, V.
Author Affiliation: Abteilung für Klinische und Experimentelle Endokrinologie, Universitätsfrauenklinik Göttingen, Robert Koch-Strasse 40, 37075 Göttingen, Germany.
Editors: No editors
Document Title: Planta Medica, 2003 (Vol. 69) (No. 10) 945-947

Abstract:
Recent cell culture experiments indicated that extracts of V. agnus-castus (VAC) may contain yet unidentified phytoestrogens. Estrogenic actions are mediated via oestrogen receptors (ER). To investigate whether VAC compounds bind to the currently known isoforms ERα or ERβ, ligand-binding assays (LBA) were performed. Subtype specific ER-LBA revealed a binding of VAC to ERβ only. To isolate the ERβ-selective compounds, the extract was fractionated by bio-guidance. The flavonoid apigenin was isolated and identified as the most active ERβ-selective phytoestrogen in VAC. Other isolated compounds were vitexin and penduletin. These data demonstrate that the phytoestrogens in VAC are ERβ-selective.



Vitex agnus castus L., - traditional drug and actual indications

Karl Peter Odenthal *
Pharmacology, Experimental Research, Madaus AG, Ostmerheimerstraße 198, D-51101 Köln, Germany


*Correspondence to Karl Peter Odenthal, Pharmacology, Experimental Research, Madaus AG, Ostmerheimerstraße 198, D-51101 Köln, Germany

Keywords
Vitex agnus castus L. • ethanol seed extract • endocrinological activity • female cycle disorders • prolactin inhibition


Abstract
There is a long tradition for the use of different preparations of drugs of Vitex agnus castus in complementary medicine in Europe. The indications in disorders of the female sexual cycle have been confirmed by experimental and clinical results. The activity of hitherto unidentified constituents of the ethanol seed extract could be localized within the pituitary-gonadal axis. Research in pituitary cell assays further elucidated a dopaminergic inhibition of prolactin synthesis and/or release. The effective administration of ethanol seed extracts against mastodynia and symptoms related to female cycle disorders with concomitant hyperprolactinaemia has been documented and awaits further establishment. © 1998 John Wiley & Sons, Ltd.

ozzman
I'm well aware of Vitex uses, particularly for lowering prolactin...however the studies posted above don't say anything about an increase in LH. Also those studies do not mention anything about Vitex effects in men
SupremeSportsEnhancements
QUOTE(ozzman @ Feb 6 2008, 01:29 PM) [snapback]455095[/snapback]
I'm well aware of Vitex uses, particularly for lowering prolactin...however the studies posted above don't say anything about an increase in LH. Also those studies do not mention anything about Vitex effects in men


Vitex has been shown in numerous studies to increase LH in both MEN and WOMEN, just like Clomid. Most of the studies done on Vitex(as with Clomid) were performed on females.
Par Deus
QUOTE(Lost Metal @ Feb 4 2008, 01:12 PM) [snapback]454487[/snapback]
I just want to spread some Febuary awareness and
remind everyone of something very simple.

Be careful what supplement companies you buy from!

We spend so much time researching supplements,
don't overlook researching brands too.

There has been some rumours floating around a
couple various forums I visit, you've all probably seen
a hint about it too.


Just because of some of the people I know well who do a lot of testing of products, and because speaking publically about lab results = getting sued, things are much worse than you guys have any idea of. Even posted CofA's don't always mean a thing because it is not like they are hard to fake -- and, people certainly do fake them.

Things are made even more complicated by the need to keep proprietary information exactly that because this is such a copy-cat industry with such poor IP protection.






Par Deus

To be fair though, the original Avant Labs products (Lipo-Y, 4-ADerm, T-G) that were sold only directly from our site as "betas" with the black and white home printer beta labels for our first several months actually were made in my kitchen.

justinjustin
QUOTE(Lost Metal @ Feb 4 2008, 04:12 PM) [snapback]454487[/snapback]
I just want to spread some Febuary awareness and
remind everyone of something very simple.

Be careful what supplement companies you buy from!

We spend so much time researching supplements,
don't overlook researching brands too.

There has been some rumours floating around a
couple various forums I visit, you've all probably seen
a hint about it too.

That some of the new emerging and fastly rising supplement
companies are actually based out of home garages and
living rooms. These are not the type of environments
that insure quality.

If your going to put something into your body to help
you gain muscle or lose fat, you don't want it to be
contaminated, dirty, or mislabeled entirely, right?

Some of my favorite and highly trusted brands are,
Avant Labs
Ergopharm
Primaforce
Giant Nutrition
Designer Supplements
Avant Research


I prefer to buy from companies who do not make promises in magazines. I like all of the companies you listed.
snipe
QUOTE(justinjustin @ Mar 4 2008, 12:44 PM) [snapback]463491[/snapback]
I prefer to buy from companies who do not make promises in magazines. I like all of the companies you listed.



How do you guys feel about Life Extension's products?
Vitamin Shoppe brand?

SteveSliwa
QUOTE(snipe @ Mar 5 2008, 06:13 PM) [snapback]463847[/snapback]
How do you guys feel about Life Extension's products?
Vitamin Shoppe brand?


Both top notch. LEF is probably better on a few things.

I have to disclose I worked with VS for awhile.
damici
I remember reading recently that the Vitamin Shoppe brand's women's multi was found by lab tests to have LEAD in it. That made me wary of ever buying any VS brand product again.

QUOTE(SteveSliwa @ Mar 5 2008, 07:20 PM) [snapback]463849[/snapback]
Both top notch. LEF is probably better on a few things.

I have to disclose I worked with VS for awhile.

Dopamine
QUOTE(damici @ Mar 6 2008, 04:50 PM) [snapback]464090[/snapback]
I remember reading recently that the Vitamin Shoppe brand's women's multi was found by lab tests to have LEAD in it. That made me wary of ever buying any VS brand product again.


The results were, I believe, from consumerlabs.com MSNBC subsequently ran an article about the lead-containing multivitamins from Vitamin Shoppe -

QUOTE
Of 21 brands of multivitamins on the market in the United States and Canada selected by ConsumerLab.com and tested by independent laboratories, just 10 met the stated claims on their labels or satisfied other quality standards.[

Most worrisome, according to ConsumerLab.com president Dr. Tod Cooperman, is that one product, The Vitamin Shoppe Multivitamins Especially for Women, was contaminated with lead.

"I was definitely shocked by the amount of lead in [this] woman's product," he said. "We've never seen that much lead in a multivitamin before."


Other products contained more or less of a particular vitamin than listed on the label. And some did not dissolve in the correct amount of time, meaning they could potentially pass through the body without being fully absorbed.

"Half the products were fine, half were not," said Cooperman.


A company emphasis on quality control and open access to laboratory results is a good buying standard, as the Vitamin Shoppe and other supplement contamination stories suggest.
SteveSliwa
QUOTE(damici @ Mar 6 2008, 04:50 PM) [snapback]464090[/snapback]
I remember reading recently that the Vitamin Shoppe brand's women's multi was found by lab tests to have LEAD in it. That made me wary of ever buying any VS brand product again.


Every company is not perfect nearly all drug, food, and supplement companies will have trace amounts of this or that from time to time but you're an idiot if concerns you as this is old news. Unless there is a massive amount something that will actually make you sick then there may be some concern.

VS does not make most of their line so the problem is probably not with them but their cm.

Regarding CL most of their testing methods are flawed and they have been sued for their inaccurate tests. I would take their statements with a grain of salt.
D Sade
Perhaps they misheard "women need supplemental iron" as "women need supplemental lead"....I mean, seriously...is it that much of a difference anyway?
Dopamine
QUOTE(D Sade @ Mar 6 2008, 07:29 PM) [snapback]464123[/snapback]
Perhaps they misheard "women need supplemental iron" as "women need supplemental lead"....I mean, seriously...is it that much of a difference anyway?


Between iron and lead? yes. /sarcasm detector

Consumerlabs is well-respected for supplement testing, but often come into conflict with companies that don't like the results they publish.
Ras
QUOTE(D Sade @ Mar 6 2008, 10:59 PM) [snapback]464123[/snapback]
Perhaps they misheard "women need supplemental iron" as "women need supplemental lead"....I mean, seriously...is it that much of a difference anyway?


Not really, when you get right down to it. Both are essential minerals that can impede the spirit world from invading the female body when the moon is upon them.
D Sade
the only lead she should be taking is the lead in the race TO the iron...then to my SHIRTS....AMIRIGHTFELLAS??AMIRIGHT??


/Wimmins be shoppin
SteveSliwa
QUOTE(D Sade @ Mar 6 2008, 07:29 PM) [snapback]464123[/snapback]
Perhaps they misheard "women need supplemental iron" as "women need supplemental lead"....I mean, seriously...is it that much of a difference anyway?


This is all amusing to me. It's like a company testing some fish and proclaiming it's going to kill you. Our foods have far more lead than you could probably consume in any supplement. The FDA should have rules no stronger than those currently used in food.

Consumer Labs is run by former FDA officals and is not respected by anyone who knows better.
SteveSliwa
ConsumerLab.com Attempts to Refute Independent Lab’s Results -- TRIMSPA Sets Record Straight
In late November, 2005, an independent third party laboratory refuted the trivalent and hexavalent Chromium results on TRIMSPA X32 reported in ConsumerLab.com’s Product Review: Chromium. ConsumerLab.com, in a press release issued yesterday, continued to stand behind their Report with the argument that the third party results, from American Analytical Chemistry Laboratories Corp. (AACL), are questionable due to a FDA warning letter on operating procedures and the lack of an EPA Certification.


(PRWEB) December 8, 2005 -- In late November, 2005, an independent third party laboratory refuted the trivalent and hexavalent Chromium results on TRIMSPA X32 reported in ConsumerLab.com’s Product Review: Chromium. ConsumerLab.com, in a press release issued yesterday, continued to stand behind their Report with the argument that the third party results, from American Analytical Chemistry Laboratories Corp. (AACL), are questionable due to a FDA warning letter on operating procedures and the lack of an EPA Certification.

TRIMSPA’s representative commented, “Dr. Obermeyer, of ConsumerLabs.com, is painting only a partial picture in his attempt to refute the results of an independent laboratory. He [Dr. Obermeyer] cites a warning letter issued by the FDA but neglects to mention that the warning was issued in February of 2003 and that, since that time, no additional warnings have been issued and all standard operating procedures have been closely adhered. The laboratory, in other words, is fully compliant with current GLP (Good Laboratory Procedures) as stated in the Code of Federal Regulations.”

“Furthermore,” added the TRIMSPA representative, “Dr. Zhen-Chang Charlie Li, Ph.D. and President of American Analytical Chemistry Laboratories, Corp., has retained a FDA consultant for more than 2 years to ensure compliance with all federal regulations. AACL operates according to EPA/FDA GLP guidelines, and QA/QC and SOP programs have been incorporated to ensure both consistency and accuracy of their results.”

According to the TRIMSPA, Obermeyer has not revealed the names of the Laboratories conducting their tests or their history of FDA compliance. Said TRIMSPA’s representative, “ConsumerLab.com has failed to provide a validated GLP assay under which these tests were performed, or the limits for detection. The question is not whether TRIMSPA is hiding anything, but is ConsumerLabs.com?”

The release issued by ConsumerLab.com also noted that, “Laboratories with expertise in testing for chromium and hexavalent chromium are generally EPA certified. American Analytical Chemistry Laboratories Corp. is not listed an EPA certified laboratory.”

According to Dr. Li, AACL, EPA certification was maintained by the lab from 1996 to 1999. With less than 1% of the Lab’s business requiring EPA certification, Li said, “The decision to drop the certification was purely a business one; certification costs thousands and thousands of dollars annually.”

Since its inception in 1994, AACL has been serving the Nutraceutical, Nutrition Supplement, Pharmaceutical, and Cosmetic industries. The Lab’s background was ideal for confirming or dispelling the ConsumerLab.com report findings. The Lab is professionally affiliated with and/or certified by the American Association of the Advancement of Science, AOAC International (Association of Analytical Chemists), American Botanical Council, American Chemical Society, American Oil Chemical Society, Institute of Food Technology, and is FDA Registered.

TRIMSPA agrees with Obermeyer that Chromium testing requires special techniques and highly experienced technicians testing. Said TRIMSPA’s representative, “Testing Chromium improperly can cause erroneous results (1) – including the false assumption that trivalent Chromium in supplements could include hexavalent chromium. Obermeyer failed to note that hexavalent Chromium is a man-made material that is not present in supplements. More important, none of the manufacturing processes for X32 introduce processes or ingredients that would oxidize the trivalent Chromium to a hexavalent state.”

“ConsumerLab.com,” said TRIMSPA’s representative, “would like the public to believe that a FDA warning letter issued in 2003 and the lack of an EPA certification makes AACL’s results less credible. The truth is, it doesn’t.”

TRIMSPA has a proven track record of compliance with all industry standards and stands by all its products and claims. The Company plans to take proper legal action where appropriate to help rectify the situation.

References:
1. Dietary Chromium: An Overview by Barry Mennen, M.D. Available at: http://www.luminet.net/~wenonah/hydro/crbacker.htmAccessed November 15, 2005.
http://www.prweb.com/releases/2005/12/prweb319528.htm
SteveSliwa
Industry weighs impact of ConsumerLab, CRN dispute
Joysa Winter

March 2005

While some industry experts say the Council for Responsible Nutrition’s federal complaint against Consumer Lab.com is long overdue, others are concerned the effort will create an unintended backlash against the industry.

“This will be seen in the media as the champion of the consumer — the David — vs the Goliath — the industry — fighting back because its ox is being gored,” said Mark Blumenthal, executive director and founder of the American Botanical Council (ABC). “CRN has always supported ethical manufacturing, responsible labeling and claims. I commend them for doing what they believe to be the right course of action. However, in the media, where ConsumerLab has been very successful — CRN’s action probably won’t look good.”

Roy Upton, executive director of the American Herbal Pharmacopoeia (AHP), a non-profit research group dedicated to developing quality-control standards for botanicals, offered a different view.

“I think it’s good for all such programs to be challenged,” Upton said. “I don’t know enough about ConsumerLab’s business model to comment on that, but without well-accepted industry standards, most testing is arbitrary and meaningless.”

In January, CRN filed a complaint with the Federal Trade Commission alleging that ConsumerLab, an independent tester of dietary supplements, engages in deceptive business practices by only publishing positive results of those companies that pay to have their products tested. For companies that don’t pay, negative results are highlighted and positive results are withheld.

“We are not opposed to third-party testing,” said Annette Dickinson, president of CRN. “We are opposed to this kind of business model. ConsumerLab is a business, not a watchdog — and one that intimidates manufacturers to pay for its services. We’ve heard complaints about their manner of operation for many years, but until recently, we didn’t have a complete understanding. Now, we have seen actual contracts, discussed it with our board, and received legal advice that the best way to seek a correction is to file an FTC complaint.”


Tod Cooperman, MD, president of ConsumerLab, called CRN’s allegations “false and absurd.”

“ConsumerLab.com has been at the forefront of exposing problems in the supplement industry,” Cooperman wrote to Dickinson. “We have earned the respect of consumers and health professionals not by deception but with rigorous science and transparency.”

Speaking to FF&N, Cooperman said: “We always publish all the positive and all the negative results of tests we do on our own dime. CRN gives the impression we can be bought to not publish results, but that is not true. We’ve been asked many times, but we’ve never done it.”

The FTC, which receives millions of complaints against companies each year, has not issued a response to CRN. “There is no time frame with which we have to respond,” a spokeswoman said, “but as a matter of courtesy, we will be responding to their letter.”

Some in the industry complain that ConsumerLab’s testing isn’t always fair. Ed Alstat, owner of the Eclectic Institute in Oregon, a manufacturer of about 200 herbal products, faced negative publicity from ConsumerLab last year when one of his echinacea products failed a test for polyphenol content.

“ConsumerLab found our echinacea was below the potency we claimed on the label,” Alstat said. “The problem is, the protocols they used were all standard procedures. Since ours is the whole herb, you can’t use the standard procedures because it takes longer to get that same constituent into the solution. If you test our product with the assay method we have, it passes.”


Alstat said he never heard from ConsumerLab and didn’t know his product was tested until he saw the results.

“The biggest criticism I have about such testing programs is that no one is determining if a product is effective or ineffective,” the AHP’s Upton said. “Everyone is chasing arbitrary marketing compounds that may have nothing or little to do with activity.”

Cooperman defended ConsumerLab’s testing standards, saying: “We work very hard on picking the most fair, most advanced methods. We also always send out a message before we begin testing a category, inviting industry to comment on our standards before we even begin.”

Blumenthal said he is not surprised ConsumerLab has come under fire. He served as a consultant during its first year of operation and ConsumerLab’s vice president of science, Bill Obermeyer, still serves on ABC’s board of advisers, as well as on the advisory board of AHP.

“I’ve known for quite some time people are upset with ConsumerLab,” Blumenthal said. “It was highly predictable there would be a backlash because they are calling attention to the dark side of the industry.

“However, I have been critical of how they have handled some of their information. ConsumerLab needs to be more careful in how they report negative findings because they may have sometimes undeserved negative consequences to companies that are not culpable.”

http://www.functionalingredientsmag.com/fi...strSite=FFNSite
Dopamine
QUOTE(http://www.consumerlab.com/aboutcl.asp)
ConsumerLab.com, LLC ("CL") is the leading provider of independent test results and information to help consumers and healthcare professionals evaluate health, wellness, and nutrition products. It publishes results of its tests at www.consumerlab.com — which receives over 2.5 million visits per year and in its acclaimed book ConsumerLab.com's Guide to Buying Vitamins & Supplements. CL also surveys supplement users and publish survey reports. Its research is cited frequently in the media, books, and at medical meetings. As a certification company, CL enables companies of all sizes to have their products voluntarily tested for potential inclusion in its list of Approved Quality products and bear the CL Seal. Since its founding in 1999, CL has tested more than 2,000 products, representing over 350 different brands and nearly every type of popular supplement.

INDEPENDENT TESTING OF PRODUCTS:
Types of Products Tested:
CL evaluates consumer products relating to health, wellness, and nutrition, including:
Health & Nutrition Products:
- Herbal Products
- Vitamins
- Minerals
- Other Supplements
Prescription Medications
Sports & Energy Products
Functional Foods
Foods & Beverages
Personal Care Products

From time to time, CL may evaluate additional types of products that impact consumer health, wellness, or nutrition.

Testing Programs:
Products are tested through CL's Product Reviews and its Voluntary Certification Program (previously known as CL's Guaranteed Testing and Ad Hoc Testing programs).

Product Reviews:
Product Reviews are CL's independent tests of multiple brands of products claiming to have the same key ingredient. Product Reviews have the following features:
Exclusively directed by CL.
Products tested are purchased independently by CL at the retail level (stores, mail order, online, etc.). CL does not accept product samples from manufacturers for Product Reviews and CL may select samples at any time during the year (to avoid sampling bias).
Products are selected by CL to reflect popular brands in the market as well as a selection of smaller brands.
Blinded tests are conducted by academic and commercial laboratories selected by CL for expertise in the type of testing needed for each product. These facilities are generally FDA inspected, follow GLP (good laboratory practice) protocols, are accredited by outside groups and/or participate in method validation programs. CL's expert research staff closely evaluates the work of these laboratories.
After a Product Review is completed, results for products selected for testing by CL are available online to subscribers. Products that have passed the Voluntary Certification Program (see below) are also listed in respective Product Reviews as well as posted for non-subscribers.
Brands that "Pass" may carry the CL Seal of Approval upon acceptance by the manufacturer of the CL Seal Use License Agreement (described below).
Product Reviews are repeated periodically (approximately every 24 to 36 months) for each product category. However, CL may re-test brands at any time. A change in a brand's test results will be reflected in CL's Web site and will affect eligibility for the CL certification seal.
Full reports of Product Reviews are available in Product Review Technical Reports sold by CL.

Policy Toward Manufacturers of Products that Fail to Pass CL Testing:
Manufacturers of products that fail to pass CL's testing may request a summary of CL's test results, product lot number, expiration date, and place and date of purchase for such product. This information is provided by CL at no cost within three business days of receipt of written request. CL maintains unopened reserve samples of all products that it tests. If a manufacturer of a tested product disputes CL's findings, CL will offer reserve sample for repeat testing by a third-party laboratory of mutual acceptance to the manufacturer and CL. The manufacturer will directly pay the selected laboratory. There is no charge by CL for providing and shipping the sample. CL and the manufacturer must each publicly announce results of the re-testing.

Voluntary Certification Program:
Manufacturers and distributors interested in the potential of having their products certified by CL, listed among the Approved Quality Products in CL's Product Reviews and bear the CL Seal may participate in the Voluntary Certification Program. Testing is conducted in the same manner as Product Reviews with test samples not accepted directly from the manufacturer.

There is a testing fee paid by the manufacturer and results are proprietary to the manufacturer. However, if a product "Passes," it may appear in CL's Web site listing of the respective Product Review with a footnote indicating that it was tested through the Voluntary Certification Program. A product that "Passes" is also eligible to carry the CL Seal of Approval upon acceptance by the manufacturer of the CL Seal Use License Agreement (described below).

Due to economies of scale, testing fees are lower for products that fall within a category about to undergo a Product Review. Manufacturers and distributors should contact lisa.sabin@consumerlab.com if they wish to be alerted to upcoming Product Review categories.

Multi-Label Testing Program:
For manufacturers of private label and multi-brand products seeking to participate in CL's Voluntary Certification Program, CL offers the Multi-Label Testing Program option. Manufacturers must provide proof that the formulations are identical for all products and all sampled products must pass testing for products to be listed as Approved Quality.

Raw Material & Private Label Certification Program:
Suppliers of ingredients to manufacturers may have their materials evaluated by CL using the same testing methods employed in Product Reviews. If the material passes testing, a Certificate of Approved Quality is issued to the supplier, who may use it in its marketing to clients and prospective clients.

Athletic Banned Substances Screening Program:
Manufacturers, sports associations, and others may have dietary supplements and nutrition products tested for substances that could result in an athlete being disqualified from competing in Olympic or other competition. The screening program includes testing for certain stimulants, narcotics, anabolic agents, diuretics, masking agents, and beta-blockers based on the Olympic Movement Anti-Doping Code or the codes of other sports associations. Such products can also be evaluated for their active ingredients using the same criteria and testing methods employed in Product Reviews.

There is a testing fee paid by the requestor, to whom the results are proprietary. However, if a product "Passes," the requestor may have it listed on CL's Web site for the respective Product Review as well as for a separate listing of products that have passed the Athletic Banned Substances Screening Program. Passing products are also eligible to carry the CL Seal of Approval upon acceptance by the manufacturer of the CL Seal Use License Agreement (described below).

Custom Analyses and Consulting:
Parties wishing to engage ConsumerLab.com's research staff to perform special purpose testing, analyses, or consulting should contact research@consumerlab.com. Examples of assignments include testing of material for clinical trials, expert analysis and opinion for litigation, and concept/product testing for new product development.


Testing Criteria and Methods:
Products are tested for the following:
Identity: Does the product meet recognized standards of quality and does the product meet the level of quality claimed on the label?
Strength (quantity): Does the product contain the amount of ingredient claimed on the label?
Purity: Is the product free of common contaminants?
Availability: Does the product break apart properly so that it may be used by the body? [See ConsumerLab.com Home Test for Disintegration for how to test your supplements]

These criteria must be met to be considered Approved by CL. If a manufacturer seeks to use the CL Seal of Approval, the product will be tested for these criteria every twelve months based on a random sample purchased on the open market.

Specific testing criteria vary by product and are selected on the basis of high consumer importance and a lack of ongoing monitoring or reporting by government or independent organizations.

CL seeks to use the most advanced and appropriate test methods. Each Product Review provides a link to the methods used. Below are examples of test methods used:
AA (atomic absorption)
CE (capillary electrophoresis)
Gas chromatography with detection by FID (flame ionization detector), ECD (electron capture detector) and MS or MS/MS
HPLC (high performance liquid chromatography) in conjunction with a variety of detection methods including IR (infra-red), photodiode array, ELSD (evaporative light scatter detector), MS (mass spectroscopy), and MS/MS (tandem mass spectroscopy)
HP-TLC (high performance thin-layer chromatography)
ICP/MS (inductively coupled plasma/mass spectroscopy)
Microscopy
MS (mass spectroscopy)

An index to the methods and standards for each Product Review is found at www.consumerlab.com/methods_index.asp.

USE OF THE "CL CERTIFICATION SEAL"
Brands that "Pass" Product Reviews, or the Voluntary Certification Program are posted on CL's Web site as having "Passed" the specific test performed. Manufacturers of brands that "Pass" may purchase a license to use the CL Seal of Approval on their product labels, packaging, promotion, and advertising according to parameters set forth in the CL Seal Use License Agreement. Such licenses expire upon established dates and automatically terminate if the product does not "Pass" any re-testing by CL. In order to continue to carry the CL Seal directly on product labeling, the product must pass retesting every twelve months.


KEY MANAGEMENT:
Tod Cooperman, M.D., President
Dr. Tod Cooperman is a noted researcher, writer, and speaker on consumer healthcare issues. Dr. Cooperman is also the Founder of PharmacyChecker.com (www.pharmacychecker.com), an evaluator of Internet pharmacies, and CareData Reports, Inc., a leading independent evaluator of consumer satisfaction with managed care (now a division of J.D. Power and Associates). Dr. Cooperman is a graduate of the Boston University School of Medicine.

William R. Obermeyer, Ph.D., Vice President for Research
Dr. William Obermeyer joined ConsumerLab.com from the U.S. FDA (Food and Drug Administration) where he was a Natural Products Chemist guiding research activities of various natural products and educating the public, academia and industry on the safety and proper manufacture and testing of dietary supplements. Dr. Obermeyer is an internationally recognized authority on pharmacognosy (the science of natural products) and serves on the Executive Board of the AOAC Technical Division for Reference Materials. Dr. Obermeyer received his Ph.D. from the Philadelphia College of Pharmacy and Science.

Lisa K. Sabin, Vice President for Business Development
Lisa Sabin joined ConsumerLab.com from Prevention Magazine where she was an Account Executive working with healthcare and consumer products companies. Prior to that, she worked for Hearst Magazines, in the Brand Development Department, managing the merchandising of products under the names of its publications, such as Popular Mechanics, Cosmopolitan and Esquire. Ms. Sabin is a graduate of Rutgers University with a degree in Communications.

Elena Suzuki Yoo, CN, Japan Manager
Elena Suzuki Yoo coordinates ConsumerLab.com's activities in the Japanese market. Ms. Yoo brings experience in international business and Japanese medical/nutritional writing and translation. Ms. Yoo holds a Certified Nutritionist degree from the American Health Science University in Colorado and a B.A. from Japan Women's University (Nihon Jyoshi Daigaku) in Tokyo.


OWNERSHIP, AFFILIATIONS, AND SOURCES OF REVENUE:
ConsumerLab.com, LLC is a privately held company based in White Plains, New York. It is not affiliated with manufacturers of health and nutrition products. Revenues are derived from sales of online subscriptions, books, CL's Product Review Technical Reports, advertisements on its Web site, as well as Voluntary Certification Program fees, and license fees from both the re-publication of its proprietary information and the authorized use of the CL Seal of Approval.

PUBLIC COMMENT:
CL welcomes input from any interested party (e.g., consumer groups, retailers, healthcare professionals, academic and commercial researchers, manufacturers, government agencies, trade groups, etc.) in its testing policies and procedures. Comments and questions should be submitted electronically to info@consumerlab.com.


ConsumerLab has been cited constantly in the media, medical journals and books, including -

QUOTE(http://www.consumerlab.com/inthenews.asp)
Newspapers:
Boston Globe, Chicago Sun-Times, Chicago Tribune, Gannett News Service, Investor's Business Daily, Minneapolis Star Tribune, Newsday, New York Post, Pittsburgh Post-Gazette, Reno Gazette-Journal, San Francisco Chronicle, The Arizona Republic, The Atlanta Constitution, The Atlanta Journal-Constitution, The Baltimore Sun, The Christian Science Monitor, The Detroit Free Press, The Hartford Courant, The Journal News, The Los Angeles Times, The New York Times, The Oregonian, The Orlando Sentinel, The Seattle Times Magazine, The Tampa Tribune, The Wall Street Journal, The Washington Post, USA Today, and Wilmington Morning Star.

Magazines:
Arthritis Today, Better Homes and Gardens, Business Week, Cooking Light, Fitness Magazine, Glamour Magazine, Health Magazine, HerbalGram, Herbs for Health, Kiplinger's Personal Finance, Ladies' Home Journal, Men's Health, Modern Maturity, Money Magazine, Mother Earth News, New Choices Magazine, Newsweek International, O the Oprah Magazine, Parade, Prevention Magazine, Pure Power, Magazine Protégez-Vous, Reader's Digest, Remedy Magazine, Runners World, Self, Shape, Time, USA Weekend, U.S. News and World Report, and Vegetarian Times

Newsletters:
AARP Bulletin, Bottom Line Health, Bottom Line Personal, Cosmetics Cop Newsletter, Dr. Andrew Weil's Self Healing Newsletter, Environmental Nutrition, Nutrition Action Newsletter, The Johns Hopkins Medical Letter — Health After 50, The Tufts University Health & Nutrition Letter, Townsend Letter for Doctors and Patients, and the UC Berkeley Wellness Letter

Radio:
"Eye on the Internet" (KRLD 1080/Dallas-Fort Worth); Focus on the Family with Dr. James Dobson; National Public Radio (NPR) All Things Considered, Morning Edition, and Talk of the Nation; The People's Pharmacy (Public Radio); Leonard Lopate Show (WNYC - New York); HealthTalk with Dr. Hoffman (WOR).

Television:
ABC News 20/20, CBS Evening News with Dan Rather, CNN Headline News, and NBC Today Show and Weekend Today Show.

Trade & Professional Publications:
American Journal of Nursing, Complementary Practice of Alternative Medicine, Drug Store News, Food Labeling and Nutrition News, Functional Foods, Health Supplement Retailer, Journal of Practical Psychiatry, NACDS Chain Pharmacist Practice Memo, Natural Business, Natural Pharmacy, Nutraceuticals World, Nutritional Outlook, Primary Psychiatry, Psychiatric Annals, The Tan Sheet, Today's Dietician, Today's Health & Wellness, U.S. Pharmacist, Vitamin Retailer Magazine, and Whole Foods.

Books:
"Nutrition Concerns in Women" by Sarah Johnston Miller, Pharm.D., BCNSP appearing in the American College of Clinical Pharmacy's Pharmacotherapy Self-Assessment Program version IV, 2002.
The Wellness Revolution, Paul Zane Pilzer, John Wiley & Sons, 2002.
Nutritional Aspects and Clinical Management of Chronic Disorders and Diseases, Edited by Felix Bronner, CRC Press, 2002.
Reader's Digest Cut Your Cholesterol, David L. Katz, M.D. and Debra L. Gordon, Reader's Digest Association, Inc., 2004
Natural Causes, Dan Hurley, Broadway Books, 2006
The World's Greatest Treasury of Health Secrets, BottomLine Books, 2006
What to Eat: An Aisle-by-Aisle Guide to Savvy Food Choices and Good Eating, Marion Nestle, North Point Press, 2006
What Your Doctor Hasn't Told You And The Health Store Clerk Doesn't Know, Edward L. Schneider, M.D. and Leigh Ann Hirschman, Penguin Group, 2006
Understanding Dietary Supplements, Jenna Hollenstein, MD, RD, ELS, University Press of Mississippi, 2007
SteveSliwa
If people stopped buying every company that had a minor or even major problem at some point we would have far less choices for food, supplements, and drugs.

http://www.fda.gov/opacom/7alerts.html
http://www.fda.gov/oc/po/firmrecalls/archive_2007.html

Palo Alto Labs
Whole Foods Market
Annie's Naturals
Frito-Lay
Trader Joe's
Campbell
Kraft Foods
even baby food Gerber

Issues with food concerns are always far greater than supplements.
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