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Mind and Muscle Forums > Chemically Correct > Anabolics & Performance Enhancers
methodice
Ok.

So I read about halodrol in another thread. "Halodrol is fairly slow acting, most are reporting cycles of 4-6 weeks to report any performance increase."

I have read about people that are doing these hormonal substances but I don't understand why some take a long time to manifest noticeable changes, while other substances are faster.

What is happening within the body in the first 3-4 weeks of use?
SupremeSportsEnhancements
QUOTE(methodice @ Feb 12 2008, 12:43 AM) [snapback]456761[/snapback]
Ok.

So I read about halodrol in another thread. "Halodrol is fairly slow acting, most are reporting cycles of 4-6 weeks to report any performance increase."

I have read about people that are doing these hormonal substances but I don't understand why some take a long time to manifest noticeable changes, while other substances are faster.

What is happening within the body in the first 3-4 weeks of use?


For injectable steroids, it is the particular ESTER that determines the rate of release and thus, the rate at which one will experience effects. The Propionate ester is a fast-acting ester which will provide fast results, while Enanthate and Decanoate are long-acting esters which provide a slower release and thus a slower mainfestation of effects.

As for oral steroids, each one is active upon the very first dosage administration. However, depending on how anabolic or androgenic a particular compound is, the rate at which results MANIFEST will vary signifincantly. Anadrol, which is extremely anabolic and androgenic, will provide the user almost instant results, whereas Oral Winstrol or Anavar may take several weeks to fully notice effects.
methodice
QUOTE(SupremeSportsEnhancements @ Feb 11 2008, 10:23 PM) [snapback]456777[/snapback]
As for oral steroids, each one is active upon the very first dosage administration. However, depending on how anabolic or androgenic a particular compound is, the rate at which results MANIFEST will vary signifincantly. Anadrol, which is extremely anabolic and androgenic, will provide the user almost instant results, whereas Oral Winstrol or Anavar may take several weeks to fully notice effects.


Yeh I am sorta wondering why it varies between substances.
SupremeSportsEnhancements
QUOTE(methodice @ Feb 12 2008, 02:38 AM) [snapback]456782[/snapback]
Yeh I am sorta wondering why it varies between substances.


As I stated:

As for oral steroids, each one is active upon the very first dosage administration. However, depending on how anabolic or androgenic a particular compound is, the rate at which results MANIFEST will vary signifincantly. Anadrol, which is extremely anabolic and androgenic, will provide the user almost instant results, whereas Oral Winstrol or Anavar may take several weeks to fully notice effects.
skigazzi
QUOTE(methodice @ Feb 12 2008, 01:38 AM) [snapback]456782[/snapback]
Yeh I am sorta wondering why it varies between substances.


Basically, halodrol is pretty weak stuff that takes weeks before you can tell you are actually on something, as is 1,4AD . But their sides are much milder as well.

babyblu
QUOTE(methodice @ Feb 12 2008, 01:38 AM) [snapback]456782[/snapback]
Yeh I am sorta wondering why it varies between substances.



I think you really answered your own question if you implied the word 'different' before the word 'substances'. Different chemicals have different effects. There are several different AAS compounds. They have different chemical properties and therefore different effects upon the human body.

bb
methodice
Yeh different. But why.

Lets make it simple. We have your supp which has halo and epi in it.

Why does halo only show effects later in the time period whereas, the epi has been reported to kick in earlier? It's more than just the purported Anabolic/androgenic ratio right?
SupremeSportsEnhancements
QUOTE(methodice @ Feb 13 2008, 12:28 AM) [snapback]457011[/snapback]
Yeh different. But why.

Lets make it simple. We have your supp which has halo and epi in it.

Why does halo only show effects later in the time period whereas, the epi has been reported to kick in earlier? It's more than just the purported Anabolic/androgenic ratio right?


NO, it is NOT more than the "purported Anabolic/androgenic ratio".

Both steroids are IMMEDIATELY active, results simply take TIME to MANIFEST.
methodice
Oh yeh my use of purported was meaning supp companies claim epi has 12:1 anabolic andro ratio or something, but do they actually do studies that show this?

"Both steroids are IMMEDIATELY active, results simply take TIME to MANIFEST"

Why does the halo take a longer TIME?

They are active immediately you say, I know after the receptor ligand interaction genetic and protein transcription or something like that occurs so the effect of the one dose starts soon but last for many hours not just dependent on half life, but also gene/protein modulation.

To me it seems you should be able to notice changes within the first week, if not a day or two...so I don't get it.

Is there a critical mass effect that occurs on week 3-4 with halo?
SupremeSportsEnhancements
QUOTE(methodice @ Feb 13 2008, 01:23 AM) [snapback]457022[/snapback]
Oh yeh my use of purported was meaning supp companies claim epi has 12:1 anabolic andro ratio or something, but do they actually do studies that show this?

"Both steroids are IMMEDIATELY active, results simply take TIME to MANIFEST"

Why does the halo take a longer TIME?

They are active immediately you say, I know after the receptor ligand interaction genetic and protein transcription or something like that occurs so the effect of the one dose starts soon but last for many hours not just dependent on half life, but also gene/protein modulation.

To me it seems you should be able to notice changes within the first week, if not a day or two...so I don't get it.

Is there a critical mass effect that occurs on week 3-4 with halo?


Halodrol is a VERY MILD 4-chlorodehydromethyltestosterone derivative, it is WEAK, and that is why it takes TIME for RESULTS to MAINFEST THEMSELVES. It is neither highly anabolic or androgenic. However, the steroid is active and working it's magic from DAY ONE.

Anadrol however, is extremely anabolic AND androgenic, and thus, results will mainfest themselves almost immediately.
Heavy_Lifter85
QUOTE(SupremeSportsEnhancements @ Feb 13 2008, 12:39 AM) [snapback]457037[/snapback]
Halodrol ... the steroid is active and working it's magic from DAY ONE.


So this is simple a matter of perception on the part of the user, i.e. the weight gain is slow enough that a user doesn’t notice the change in the mirror. Then he sees an old friend who remarks, “Wow, looks like you gained XX lbs on a halodrol cycle!” But don't people generally weigh in regularly when logging this type of thing? A slow and steady weight gain should be apparent from the scale readings.

----------------------------------------------------------------------------------

Suppose I gain 12 lbs on a 6 week halodrol cycle. Does it happen like scenario A or scenario B? (I’m not concerned with actual numbers here, just trends)

A)week 1 up 2lbs; week 2 up 4 lbs total; week 3 up 6 lbs total, week 4 up 8 lbs total; week 5 up 10 lbs total; week 6 up 12 lbs total

B)week 1 up 0.1lb; week 2 up 0.2 lbs total ; week 3 up 0.3 lbs total; week 4 up 4 lbs total; week 5 up 8 lbs total; week 6 up 12 lbs total


In scenario A, the weight gain could be slow enough that a user doesn’t notice the change in the mirror. Then he sees an old friend who remarks, “Wow, looks like you gained XX lbs on a halodrol cycle!” Unless the user has been weighing in all along, which leads us to scenario B.

Scenario B seems implausible in that I don’t see a biological mechanism to explain it. Did the user finally get his training and diet dialed in? What else could explain this?
maggmaster
There appears to be a bit of a disconnect here. I believe that the disconnect lies in most peoples desire to know why scientifically versus anectdotally. We all understand that some steroids take longer to manifest results, can anyone tell us WHY with a scientific explanation? My personal theory would be based on satelite cell activation and manipulation but I have no studies to back that up at the moment.
SupremeSportsEnhancements
QUOTE(maggmaster @ Feb 13 2008, 08:42 AM) [snapback]457078[/snapback]
There appears to be a bit of a disconnect here. I believe that the disconnect lies in most peoples desire to know why scientifically versus anectdotally. We all understand that some steroids take longer to manifest results, can anyone tell us WHY with a scientific explanation? My personal theory would be based on satelite cell activation and manipulation but I have no studies to back that up at the moment.


You guys are overcomplicating the issue, it simplyu comes down to the Anabolic/Androgenic PROPERTIES of a particular steroid:

HIGHLY ANABOLIC AND/OR ANDROGENIC STEROIDS produce FAST results:

Testosterone Suspension
Anadrol
Dianabol
Trenbolone Acetate
Halotestin
Superdrol
Pheraplex

MILD AAS WITH LITTLE ANABOLIC AND/OR ANDROGENIC ACTIVITY produce SLOW results:

Anavar
Winstrol
Turinabol
Halodrol
Faruzabol
Primobolan Acetate

Archaic
It does takes time for the anabolic machinery so to speak to 'kick in'. For example, you could take test prop or suspension every day and despite the short halflife, it would still take weeks to a month to manifest full effect. For example, changes in your hematocrit brought about by androgenically mediated RBC production take time, and will effect your vascularity, endurance, and the overall 'feel' effect of a cycle.

Its a blanket statement to say that androgenic drugs manifest fast results and anabolic ones manifest slow results.. They are both 'working' at the same speed, you just don't notice your muscles laying down new muscle as quickly as you notice your blood pressure and strength and aggression increase.

Also drugs which are estrogenic will typically produce a more rapid 'feel effect' from a cycle because you'll hold water and it will cause weight gain, which will make you think you're getting gains. Some people confuse result for this being an effective compound.

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