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Colin
QUOTE(Spook @ May 17 2004, 07:25 AM) [snapback]151187[/snapback]
See this is a tough one. I can't give you a simple yes/no answer. I can break it down for you and let you decide.

On one hand as PA pointed out when discussing GPA in relation to Syntrax Swole it is counter productive to take GPA and creatine at the same time as they compete for uptake at the cellular level. So thats one strike against using them at the same time.

On the other hand the only real downside to phenogen is possible AMPK activation in Type II fast twitch fiber. This could be combated with phosphate sources like IP-6.

---------------------------------------
My take is as follows:

It makes alot of sense for a very lean person to use IP-6 along with phenogen when cutting or clean bulking. Creatine not so much. This is why I said I was curious in seeing what would happen if someone very lean used phenogen with leptigen. Theoretically you would get the best of both. You would get upregulation of oxidative tissue because IP-6 and phosphate sources don't effect that tissue much (when creatine is eliminated anyway). And the increase in phospates along with the other stuff in leptigen (origional/basic) should help counteract phospate loss in glycolytic fast twitch fibers. But its to theoretical which is why I recomended you and fletch not try it pre contest.

If I were a lean person useing this on a clean bulk I would definantly add IP-6 at a minimum or prepherably leptigen. Of course small dose of creatine in leptigen and the GPA in phenogen will fight it out a little bit reducing eficacy mildly. I however would not use creatine.

Then post use I would add Leptigen and additional creatine like nitrojet or Kreatine Ultra.

For an overweight person I would do exactly as I recomended in the article. Stack phenogen with rebirth. Then post phenogen cycle use creatine and maybe IP-6.




QUOTE(Spook @ Jun 13 2004, 07:54 AM) [snapback]159379[/snapback]
If cutting and over 13-15% body fat in men (add 10 for women) the you should use both. I am sorry if it was not clear from my writeup but phenogen is ment to be stacked with stimulant based lipolytic supplements. One of the bigest benefits of Phenogen is increased Beta-AR density in skeletal muscle which makes HEAT/ECA/Other work even better. So its ment to be stacked.

If I had made it a cutting only supp it would have contained stimulants and NE potentiators. But I wanted it to be useful as an anti-fat gain agent as well and stimulatns would be counter productive for that purpose. So again I assumed anyone useing phenogen on a cut would also be useing HEAT, or ECA, or something like that.

If cutting below 13-15% then I would not use phenogen.

If bulking use phenogen alone without stimulants.

methodice
Thanks Colin for digging this up. quigs has mentioned in another thread about his personal experience with GPA and creatine being beneficial in some way. Maybe he can chime in.

For those that don't know:

Leptigen rebirth:

l-histadine, IP6, lecithin, inositol. acetyl-l-carnitine, l-arginine, n-acetyl-cysteine, simmondsin, alpha lipoic acid, synephrine, biotin, and 10% flavoring.

From Spook's writeup:

"Men or women who are already lean and want to bulk up while minimizing fat gain:

This time around use what ever bulking diet you like.

Stack Phenogen with Leptigen Mass and eat at approximately 500 calories above maintiance. If you’re going to be particularly bad about your diet on any given day stack with 120mg of Vanadium Sulfate, up to 1g of alpha lipoic acid, and full dosing of Sesathin. That dose of Vanadium is not to be used on a regular basis.

Again use for a maximum of six to eight weeks at a time. Take two to four weeks off and use creatine monohydrate and possibly a source of phosphates like IP-6."

Leptigen mass:

IP6, betaine HCl, creatine pyruvate, lecithin, inositol, l-leucine, l-histadine, l-taurine, sodium acetate, acetyl-l-carnitine, glucosamine HCl, ascorbyl palmitate, n-acetyl-cysteine, vitamin E acetate, alpha lipoic aicd, biotin, and 10% flavoring.
Jakeshorts
Even if some of these products aren't around anymore how plausible is it to think that custom cap. could mix us up some generic versions? Redsky?
Colin
QUOTE(Jakeshorts @ Mar 19 2008, 02:40 AM) [snapback]466639[/snapback]
Even if some of these products aren't around anymore how plausible is it to think that custom cap. could mix us up some generic versions? Redsky?


Not all that plausible,considering we don't have the proper amounts of the actives established.

I would guess that Par would be willing to sell the formula to Custom Capsule.
Jakeshorts
QUOTE(Colin @ Mar 19 2008, 10:44 AM) [snapback]466668[/snapback]
Not all that plausible,considering we don't have the proper amounts of the actives established.

I would guess that Par would be willing to sell the formula to Custom Capsule.



Seems a little ridiculous to say it's not at all plausible considering we could certainly guess and try a formula. If the price were comprabable to leptigen I'd say it's be a fucking helluva deal. Obviously we're not talking perfection, but I'm a little skeptical the original forumla was the end all be all of partitioning effects to be had with the same mechanisms.

Based on my response my question was a bit rhetorical. It's absolutely plausible and certainly worth looking into.
Colin
QUOTE(Jakeshorts @ Mar 19 2008, 06:50 AM) [snapback]466671[/snapback]
Seems a little ridiculous to say it's not at all plausible considering we could certainly guess and try a formula. If the price were comprabable to leptigen I'd say it's be a fucking helluva deal. Obviously we're not talking perfection, but I'm a little skeptical the original forumla was the end all be all of partitioning effects to be had with the same mechanisms.

Based on my response my question was a bit rhetorical. It's absolutely plausible and certainly worth looking into.


Well,I actually replied with "not all that plausible" and "not at all plausible" so for the most part I'm in agreement with you.

However,I think a large part of the effects were realized because of the ratios of the actives used so guessing may not yield comparable results with the original.Getting Custom to re-release the Leptigen line in arrangement with Avant would be very,very preferable but if this fails to manifest itself into reality I do think that the guessing approach warrants looking into.

Par has spoke before of selling the Leptigen formulas to another company when Avant production on them ceased as he did not plan on putting Leptigen back on the market as people couldn't grasp onto the science behind it i.e.they were too stupid.

I do remember that Leptigen original and subsequent releases sold out at the Avant store and Bulknutrition quickly.

Par has indicated that the bulk dealings between Avant and NP have gone sour so CC seems like the guy to go to on this.
Jakeshorts
good thing you're an avant representative. Mention something to him tomorrow while you're sprinkling Slenda on his corn flakes wink.gif
Kimbo
One can take a pretty good guess based on the order of the ingredients and what the product supposed to do. For example, look at the ingredients for LG Mass:

IP6, betaine HCl, creatine pyruvate, lecithin, inositol, l-leucine, l-histadine, l-taurine, sodium acetate, acetyl-l-carnitine, glucosamine HCl, ascorbyl palmitate, n-acetyl-cysteine, vitamin E acetate, alpha lipoic aicd, biotin, and 10% flavoring.

Now, based on what it does, you could take a pretty good guess at the following:

- include enough lecithin to increase leptin sensitivity
- include enough l-leucine to increase protein synthesis
- include enough sodium acetate to help with partitioning
- include enough glucosamine HCl to increase leptin signalling

etc. There are lots of threads on many of these substances on here, so if you do a search you can figure much of it out.

Jake, the down side to capping this stuff is that it would be a lot of caps. IIRC a dose of LG was about 10-15g.
Colin

QUOTE(Jakeshorts @ Mar 19 2008, 07:05 AM) [snapback]466678[/snapback]
good thing you're an avant representative. Mention something to him tomorrow while you're sprinkling Slenda on his corn flakes wink.gif


Done.
Odium
QUOTE(Colin @ Mar 19 2008, 11:01 AM) [snapback]466677[/snapback]
Par has indicated that the bulk dealings between Avant and NP have gone sour

WTF mad.gif
Colin
QUOTE(Odium @ Mar 19 2008, 07:56 AM) [snapback]466707[/snapback]
WTF mad.gif


Yees,note that NP is no longer offering bulk Sesathin,bulk Lipo-Y carrier etc...

This makes Colin a sad panda bear,too sad.gif
SupremeSportsEnhancements
AndroGenerator conatins CEEM and GPA, you guys should give it a shot smile.gif
Jakeshorts
considering this thread is about how creatine shouldn't be used with GPA announcing your product does just that was pretty fucking stupid. Don't learn from past mistakes do you?
habit
QUOTE(Jakeshorts @ Mar 19 2008, 09:49 AM) [snapback]466745[/snapback]
considering this thread is about how creatine shouldn't be used with GPA announcing your product does just that was pretty fucking stupid. Don't learn from past mistakes do you?


LMAO
Kimbo
Wow.
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