Anyone seen this yet? I got an email from the USPLabs Inner Circle about this being released and picked up a bottle on a whim. Should be arriving shortly. In the meantime, here are the specs, filled with some outlandish claims as usual (not hating, I really like every USP product I've tried...but come on...why do you want to sound like Muscletech?) Doesn't really help their cause when their "transformations" look like they involve only a bit of sodium manipulation and a few hours in a tanning bed.

Sorry, couldn't dig up a legit ingredient profile since the site for this from the site.

The link the write-up: http://www.usplabsdirect.com/catalog/produ...3bd5282897a6edd

Here's The 23 Immediate Ways Recreate™ Will Rip Fat Off Your Body:

1. Increase Norepinephrine By 75%! – Norepinephrine is known as THE primary fat burning hormone – A key ingredient in Recreate™ increases norepinephrine levels by 75% so fat flies off your body!

2. Activates Fat Burning Enzyme – On the inside of a fat cell, there is another enzyme called Hormone Sensitive Lipase (HSL) which mobilizes stored fat to be broken down and used for energy. Recreate™ effectively activates HSL so that the fat can be mobilized and burned; this is an amazing feat accomplished in fat burning supplementation.

3. Increases Thyroid Output By 250% -Recreate's™ special extract has been proven to send thyroid output through the roof so your body functions like an industry-sized furnace!

4. Promotes Conversion of T4 to T3 - In addition to stimulating the secretion of primarily T4 from the thyroid, a key ingredient in Recreate™ promotes the conversion of the relatively inactive T4 to its potent metabolite T3!...T3 is like unlocking the special fat loss code: turning on your blazing metabolism and incinerating the fat right off of your body.

In stressful conditions T4 to T3 conversion is all but non-existent. And let's face it, with work, your job, your family, school & workouts, your life is full of stress - so your ability for fat loss is significantly hindered. Recreate™ takes care of all that!

5. Automatically Promotes "Clean" Eating – Users of Recreate™ automatically eat healthier foods. Cravings for junk food are drastically reduced. It's automatic will power!

6. Increases Testosterone Production – Increasing testosterone during a period of fat loss is very favorable for many reasons: 1) Testosterone is a hormone that promotes fat loss. 2) Testosterone promotes muscle building. 3) Often, when calories are lowered, libido is also lowered -- the testosterone increase from Recreate™ will help put your libido in overdrive!

7. Appetite Suppression– In-house studies show you'll eat up to 23% less!

8. Liberates Fat From Fat Cells Into The Blood Stream To Be Burned For Fuel – Recreate's™ synergistic formula allows for stored fat to be removed and placed into the blood stream and then burned. This is important - Just because stored fat enters the blood stream does not mean it will be burned – there's a high chance it will be re-stored as bodyfat. Just like Recreates™ 1-2 combo on thyroid output and appetite, here's an example of Recreates™ synergistic formula in action on ugly, unwanted bodyfat.

9. Increase Lean Muscle Tissue While Losing Fat –Unfortunately, most weight loss is up to 90% muscle – which leaves you soft and weak. An ingredient in Recreate™ has been proven to increase lean muscle tissue by 7.7 pounds during periods of significant fat loss! This ensures you'll be ripped & extremely muscular as well!

10. Significantly Increases cAMP – Increasing cAMP was the secret of why ephedrine was so effective for fat loss. Of course, Recreate™ contains no ephedrine and actually utilizes a more efficient and effective pathway than ephedrine to increase cAMP. Ephedrine does increase cAMP, that's how it allows for lipolysis. The difference is that ephedrine binds to the beta 2-adrenergic receptor and then in turn, activates adenlyate cyclase and causes cAMP accumulation which eventually allows for lipolysis.

The difference is that Recreate™ bypasses the step where it binds to the beta 2-adrenergic receptor and directly activates adenylate cyclase, hence this is the reason why there is no down-regulation of the beta 2-adrenergic receptor with Recreate™, unlike ephedrine. In other words, you get the awesome fat burning effects as long as you use Recreate™!

11. Promotes Insulin Sensitivity Improvement – By inhibiting 11B-HSD1 activity, intracellular glucocorticoid levels are lowered in skeletal muscle and adipose tissues, which, consequently can result in improved insulin sensitivity.

12. Precise Cortisol Control – Cortisol typically skyrockets during fat loss phases and contributes to fat being stored in "problem" areas such as the stomach and love handles. Recreate™ fights to keep cortisol low so fat loss can be promoted.
However, having very low levels of cortisol might leave you with muscle weakness, depressed lipolysis, increased cellular damage when other cells are injured, excessive oxidative damage and perhaps most importantly, a lack of cortisol could allow even a minor respiratory tract infection or a hypersensitivity reaction to cause death.

With that said, without cortisol, we can't handle physical or mental stress. Recreate™ works with your body to keep a perfectly balanced level of cortisol so extreme fat loss can be achieved without risking the aforementioned negatives.

13. Specifically Targets Fat Mobilization Around Your Abs! - The genetics of men causes fat distribution around organs. That's right, around your stomach, intestines and consequently, your abs appearance are effected. To beat genetics, Recreate™ increases the activity in those stubborn fat cells to mobilize the fat and reveal your abs!

14. Increase Energy Expenditure - This inhibition of 11Beta-HSD1 may be responsible for a built in mechanism in humans, responsible for a resistance to obesity.

When you over-consume fat, it down-regulates or decreases activity of 11B-HSD1. This is the body's adaptive response to consuming too much fat...a kind of way of the body saying, "we're taking in too much fat so let's start preventing accumulation."

Now, of course we all know you can't just eat a ton of fat and get lean. But, by inhibiting the enzyme responsible for reactivating cortisol in metabolically active tissues, it is thought to increase the amount of calories you burn.

15. Potent Anti-Catabolic Properties – Inhibits muscle catabolism. Elevations in cAMP are responsible for limiting catabolism of skeletal muscle. Muscle wasting is a characteristic of numerous disease states, as well as muscle disuse. Steroid users are all too familiar with the latter effect, when hard-earned gains rapidly disappear post-cycle. Much of this atrophy is caused by the action of the so-called calpains.

The calpains are a family of calcium dependent enzymes that degrade unused muscle tissue. Calpains in turn are inhibited by another endogenous compound called calpastatin.

Not only does Recreate™ promote anabolism, it slows muscle catabolism, even when muscle is not being used extensively. So we have another potential mechanism whereby Recreate™ starves off post cycle muscle loss.

16. Drastically Increases Lipolysis (fat burning) – Cir20x™, a novel unique ingredient in Recreate™, has been proven to increase lipolysis up to 20 times greater than caffeine...and Recreate™ is the only fat loss product in the world to have this rare compound!

17. Energy To Enhance Harder Workouts – A strong, smooth, clean feeling of energy that lasts all day without any crash will help power you through even the most intense workouts so you can rip obscene amounts of fat and get a killer set of abs!

18. Increases Hypothalamic ATP – Anyone who has ever made an attempt to lose weight knows you quickly become miserable and irritable, even if you're getting good results. This is due to a decrease in the brain of a few key "feel good" chemicals. Recreate's™ synergistic blend keep's your brain functioning optimally and you feeling great while you burn fat!

19. ORAC Value of 10,465 – Due to the potent anti-oxidative effects of Recreate™, the result is a better functioning body. This directly leads to improved immune function which is needed to keep you in the gym while trying to lose fat

20. Stimulates Thermogenesis Via an Increase In ATP consumption during certain physiologic processes (e.g., substrate cycles, Ca2+ transfer from cytosol to sarcoplasmic reticulum). Increases metabolic rate.

21. Stimulates Thermogenesis Via A Decrease In The Efficiency Of ATP synthesis via transcriptional control of genes, including those responsible for uncoupling proteins (UCPs) and mitochondrial glycerol-3-phosphate dehydrogenase (mG3PD). Increases energy expenditure.

22. Increases Lipid Metabolism Via An Increase In Adipose Tissue's Sensitivity to sympathetic nervous system-mediated lipolysis (e.g. increase beta-adrenergic receptor expression). Makes your fat cells more sensitive to the effects of norepinephrine, the hormone which stimulates fat burning.

23. Increases The Oxidation Of Fatty Acids by stimulating the expression of the enzyme carnitine palmitoyl transferase. Another pathway where Recreate™ is working to burn off those fatty acids which we released when we increased the release and breakdown of triglycerides from fat stores.

Ingredients:

Caralluma Fimbriata, Olea Europaea Extract, Coffea Arabica L. Extract , Forslean, Caffeine, Microtea Debilis Extract.

Not sure if that's the order, but that is the order they are listed in from the website.

waiting for more feedback on this recreate product

I got caught into the buying hype at the time on anabolic pump, bought a few bottles, but it's not doing much for me

Nothing special. Sure will get you wired, though.

Thanks for the ingred. list. If I remember correctly, their last IC type offering was called 'Bolic and was simply forskolin extract with a shit ton of claims made about it. However, this acts via 23 different pathways to get you hyoooj!!!

Surprised you don't get much out of AP though. I didn't really "notice" it until I stopped taking it. Oh yeah, and the wicked anterior tibialis pumps I get while running.

I bought a bottle also...I said fuck it. It was only $30. The claims that they make are pretty crazy. I guess we'll see how well this stuff actually works.

I wil be running this along side anabolic pump and blue up. I'm 160 at 9% bf. I will be running a cycle of tbol at the end of may so i want to see how well this will work. Hopefully i can lean out to 7-8% while maintaining the muscle that i have. If i can i will be very happy.

Not much on PubMed on caralluma fimbriata. Here's something:



Weird. So body weight, BMI, hip circumference, body fat and energy intake didn't change, but waist circumference and appetite went down. Makes me think that this stuff has some sort of effect on VAT?

Check out the feedback on Anabolic Minds; we sold out extremely fast because of the rave reviews it is getting. This stuff works.

Robboe mentioned this stuff to me recently. It's also known as Slimaluma and from what he said, it basically mimics CCK.

Yeah, looks like Slimaluma is a brand name for an extract of it. Looks pretty promising - stimulant-free fat loss and appetite suppression.

Country Life makes a product called GenaSlim that has EGCG and Slimaluma.

I believe NOW makes one also. I'm thinking of trying it out as part of a very short term PSMF.

As far as Recreate, I'll reserve judgment until it's actually out.

oh yeah? maybe all your testers are 100% responders to USPlabs products... but then again a poll at AM showed that there are more NON-RESPONDERS to to anabolic pump

http://anabolicminds.com/forum/supplements...t=anabolic+pump

same craze was for anabolic pump in the beginning...

Anabolic Pump is an extremely powerful supplement if it works for you. Its efficacy depends upon:

-Your genetics
-Your diet and your diet with Anabolic Pump should reflect your genetics.

There would be way less non-responders had they been able to adjust their diet appropriately. However, that is not to say that there would be no non-responders.

For more information concerning these factors, look into the Anabolic Pump manual on Anabolic Minds.

Can you please expand on how the efficacy of a nutritional supplement will depend on my genetics? And also, how exactly do you classify genetics? Good, bad, average or slow-twitch, fast-twitch, or perhaps black vs white vs brown?

This will depend on genetics as it depends on your body type and metabolism. We can classify these genetics into 3 simple categories:

-ectomorph
-mesomorph
-endomorph

Read the Anabolic Pump manual here as it will answer all your questions:

Can you really call it "the genetic equalizer" then?

AP seems to work well for me. Although a double-dose usually seems to work better for me for some reason, or one AP plus one P-Slin.

AP = great pumps and fiery dumps for me But I do like it though.

I think you are confusing genotype with phenotype. But we don't need to devolve into a petty argument about semantics as your intent was clear enough.

Has anyone here used this product or intends to? In particular I'm interested in comparisons to other products of this nature particulary DCP.

If your asking about AP, i've used 2 bottles of it and got explosive gas from it. I literally had to undo my belt cause my stomach would start bloating. I also figured being a natural fatty it wouldnt do a whole lot for me, and it didnt. I recall many years ago (~10) a supp called inzitol was released and it seemed to work in a similar way to ap.

I did order some recreate and will try it with high hopes. The original powerfull is still one of the best supps i have ever taken - the sleep was incredible.

The copy on that advert is a bit much; it even had a guy in a labcoat.

Anssi Manninen at that...

Found this study WRT to the claim for one of the other ingredients:

Yeah, I requested the full text for that Cirsimarin article in the Inner Circle forum but no one has it apparently.

What ever happened to oxidation being the bottle neck, not lipolysis?

I can prob. get that full text. I'll check tonight when I get on campus.

bump for this

Full text posted in research request/review thread in IC

Dexterium:

USPLabs indicates that Recreate is sold with a "100% Awesome Abs money back guarantee" but I can't find anything on USPLabs' website explaining how the guarantee works, where returned products should be shipped to, etc. I also cannot find any indication of a telephone number I could call with questions. Would you please explain the details of the guarantee?

Basically, we assume that you gave Recreate a legit try and if you are not satisfied with the results you have received, we will refund. As for customer service, click on the tab for customer service as it is done online. Thanks,

Dex

Apparently it's 10 years ago.

The caffeine and forskolin oxidize the FFAs once they're liberated into the blood stream. Furthermore, Recreate has an extremely high ORAC value which protects against some of the oxidative stress which can be detrimental to tissue.

Received my Recreate on Wednesday and I'm on day 2 of dosing according to directions. 2 caps in AM, 1 at noon. Will report back when I have something to report back - hopefully it's totally awesome abs.

Dex: why did you guys switch the bottles? The new bottle looks similar to the AP bottle, but appears to be much cheaper and poorly made. The shipping method sucks, btw...if you are going to package something in a fancy, glossy cardboard box, why throw it in a bubble envelope and let it get crushed to hell by USPS???? Ditch the cardboard crap and cut $2 off the price of the bottle, or something similarly useful.

Caffeine does not cause significant oxidation...lipolysis yes...but not oxidation.

what's the exact difference between forskolin and forslean? What's the dose of forslean in this product? With only one study backing it's effacacy it sounds like little questionable.

Forslean is just a standardized and trademarked extract of Forskolin. Taken from the Forslean website:

Is ForsLean different from other Coleus forskohlii extracts?

* Yes. ForsLean is the only extract of Coleus forskohlii, standardized for forskolin, that is patented for use for management of lean body mass (U.S. Patent #5,804,596 and EP #0977564) and that has been verified for potency and tested for safety and toxicity in oral, dietary supplement dosage applications

Individuals should take products that contain 250mg of ForsLean (standardized to 10% forskolin) approximately 30 minutes before meals twice daily.


The dose in ReCreate is 25mgs per 2 caps, per Jacob over @ AM. They have a big FAQ on ReCreate. Reco's on bottle is 2 caps in AM, 1 later in the day, providing 75mg total of ForSlean. I'd say that's a far cry short of reaching the 500mg reco'd by the ForSlean manufacturers.

So it's under-dosed?

Totally awesome abs for the win!

Yeah bro as far as the packaging:

-We are upgrading to better quality boxes
-I have informed CEO of the poor quality shipping and we will fix this
-The box costs pennies and has no effect on the price of the supplement

Check out this site for the difference: http://www.forslean.com/whatis.htm

As for the dose: 25 mg per 2 capsules.

This is the stuff that made cAMPHIBOLIC an effective product.

Oh you answered his question before me. Thanks

As for the dosage of forslean, I will reply with more information shortly.

What legal supplement actually causes oxidation? Don't they all basically just assist with lipolysis for the most part?

ppar alpha agonists like TTA or Sesamin

The dose is still effective and will produce results.

Im guessing that 25mg is the amount of extract, so there is 250mg of coleus in 2 caps.

That's what I was thinking too.

Jake brought up a good point about lipolysis, but I think that it's pretty cool if you can get an ingredient that causes lipolysis via a non-stimulatory pathway, as most of the supps that cause lipolysis off the top of my head are stimulatory in some fashion - caffeine and yohimbine being the big two.

We do definitely need more things that cause actual oxidation, though. Sesamin and TTA seem to be the only two options so far (unless you count DNP, but that's not exactly OTC).

Don't forget fibrates for oxidization...they aren't too difficult to come by.

yes...odd though...the more you read and research we start seeing a great effect for all of these supps for damage control...but not much in the way of fat loss specifically

I'd have to disagree. I find that oxidation is pretty common when researching things used for lipid metabolism. More specifically niacin and bezafibrate. Ancedotely I find that as long as I eat clean 200mg beza a day does some pretty amazing things. I'm actually really liking my stack right now to stay off fat acrewal during weekend binges as well as help take off fat during the week. I'll be running out of beza next week so it'll be interesting to see how it effects body composition. Beza has been shown to increase appetite but also result in lower fat acrewal. So it's a give-take sort of thing. Actually it really keeps my appetite up while taking bromo. Never a meal missed I assure you. Which is good in some regard because for me eating really eliminates (almost immediately) the sides of bromo.

My full stack can be found in my log if anyone is interested. Niacin is the leading prescribed route of lipid control.

While oxidation does need to addressed more often in supplements I think if you're willing to stack them with something else (beza, niacin) you could really see some good things happen.

As for forslean - I think this is still questionable. Not enough proof for my taste, but in bulk form (via a 15$ price tag for 50 days) I'd be willing to try it. I wouldn't say that from the "evidence" presented a reliable conclusion can be determined.

Don't know which journal this was posted in, I'm assuming it wasn't peer reviewed BUT - let's assume that the two ingredients doing all the work (hypothetical still IMO) in this supplement were to be singled out...

I'm an idiot. It says pubmed at the damn bottom...

Ever think of pulling a zsupps move and selling a cirsimarin/forslean bulk supplement or a combined cap? I think this could be extremely appealing assuming you dosed it correctly. Just having the two ingredients would allow larger more appropriating dosing and eliminate the need for a filler such as caffeine which isn't looked upon with the greatest of grandier in some circles.

Just my thoughts.

I didn't read the full-text Cirsimarin study I posted in the IC and now I can't get to it! Does the study specify which adipose tissues were sampled?

that study was originally posted by kimbo. I don't have access to full texts unfortunately. We'll see if heavy or dash etc.. chime in

For what its worth, i took my first dose today and it killed my appetite. I got the package at around 10 am, popped 2 pills and havent had anything to eat for the past 6 hours and am not hungry at all.

Argue oxidation and lipolysis all you want, it has killed my appetite on day 1 and i'll loose weight if it keeps on working well.