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Mind and Muscle Forums > Chemically Correct > Anabolics & Performance Enhancers
doom3q
http://www.msnbc.msn.com/id/3543478/

Sorry if this has been covered before, but it just started to show up on my local news.

Is this the long awaited trestolone? (MENT)
Benson
I think the big stumbling block for any hormonal male contraceptive is going to be psychological aversion to severe testicular atrophy that seems inevitable...imagine being on MENT for a year? Your nuts would be shrunk to the size of raisins...
BlackFlag
Why not just give men an Rx for plain test? You would not only have shrunken nuts on MENT, but you would probably have zero libido.....well maybe thats the idea zero libido=zero sex=no babies.
Benson
QUOTE (BlackFlag @ Apr 12 2008, 09:47 PM) *
Why not just give men an Rx for plain test? You would not only have shrunken nuts on MENT, but you would probably have zero libido.....well maybe thats the idea zero libido=zero sex=no babies.


First problem is the T has to be injected and the second problem is that at levels needed to ensure sterility, it can cause aromatization and prostate issues.

From the research I have seen so far, MENT which is methylated nandrolone, is a top candidate for this because its highly suppressive and doesn't aromatize much but is androgenic enough to keep libido and secondary sex characteristics firing. Its claimed that its also anabolic enough to prevent LBM losses.
Heavy_Lifter85
QUOTE (Benson @ Apr 13 2008, 05:28 AM) *
MENT which is methylated nandrolone


Just to clarify, MENT has a 7a-methyl group and not a 17a-methyl group.
BlackFlag
QUOTE (Benson @ Apr 13 2008, 05:28 AM) *
First problem is the T has to be injected and the second problem is that at levels needed to ensure sterility, it can cause aromatization and prostate issues.

From the research I have seen so far, MENT which is methylated nandrolone, is a top candidate for this because its highly suppressive and doesn't aromatize but is androgenic enough to keep libido and secondary sex characteristics firing. Its claimed that its also anabolic enough to prevent LBM losses.


Nandrolone is Deca right? Deca is horrible for libido...hence the term "Deca Dick" Maybe I am wrong. Is there any feedback from testers?
doom3q
QUOTE (Benson @ Apr 12 2008, 08:33 PM) *
I think the big stumbling block for any hormonal male contraceptive is going to be psychological aversion to severe testicular atrophy that seems inevitable...imagine being on MENT for a year? Your nuts would be shrunk to the size of raisins...


What spiked my interest was one patient who complained of weight gain. Ofcourse, we all know what kind of weight that was wink.gif
I never thought I'd see the day when potent androgens would be easily prescribed.

QUOTE
“I never had any real noticeable side effects. I didn’t notice any mood changes. I may have put on a little weight,” says Larry Setlow
Travis
Wtf MENT! Wow, surprised. I read a study a long time ago where various types of AAS were used in an effort to find a male contraceptive....I didnt think any of the results were conclusive however MENT may have not been used.
Benson
QUOTE (BlackFlag @ Apr 13 2008, 04:47 PM) *
Nandrolone is Deca right? Deca is horrible for libido...hence the term "Deca Dick" Maybe I am wrong. Is there any feedback from testers?

MENT does not seem to share this attribute.
doom3q
yeah, I'm starting to think it will be a combination of a progestin implant (levonorgestrel) and testosterone(TD/INJ.), which wouldn't be all that interesting.

http://www.ncbi.nlm.nih.gov/pubmed/1216147...ed_Discovery_RA
This study shows there would be no weight gain:
http://www.ncbi.nlm.nih.gov/pubmed/1586700...ed_Discovery_RA

I hope it turns out to be MENT though.
doom3q
just to make things clear, there are many studies that use MENT alone with success, so it could be anything at this point.
BlackFlag
QUOTE (Benson @ Apr 13 2008, 05:28 AM) *
First problem is the T has to be injected and the second problem is that at levels needed to ensure sterility, it can cause aromatization and prostate issues.

From the research I have seen so far, MENT which is methylated nandrolone, is a top candidate for this because its highly suppressive and doesn't aromatize but is androgenic enough to keep libido and secondary sex characteristics firing. Its claimed that its also anabolic enough to prevent LBM losses.


Pure Testosterone does not have to be injected (Androgel,Testim). Aromatization is only a problem with anabolic levels of T. Any external amount of T, will cause shut down eventually, so high levels are not needed. Pure T would just be a healthier option. Nandrolone is going to lower DHT. DHT is what is responsible for the secondary male characteristics (deep voice, facial hair, libido, penis growth, etc.) When I first when on HRT I was suppressed in a matter of weeks.
Mitosis
I was under the impression...though it may cause extremely low levels of sperm, that test does not cause consistent results with controlling pregnancy.

I heard about another drug that was working specifically on the sperm themselves....not working on the testes/HPTA. I do not know the details ....I dont remember....

Benson
QUOTE (BlackFlag @ Apr 14 2008, 09:37 AM) *
Pure Testosterone does not have to be injected (Androgel,Testim). Aromatization is only a problem with anabolic levels of T. Any external amount of T, will cause shut down eventually, so high levels are not needed.


Conversion to estrogen and DHT is an issue for some men with exogenous T even at HRT level doses.

QUOTE
Pure T would just be a healthier option. Nandrolone is going to lower DHT. DHT is what is responsible for the secondary male characteristics (deep voice, facial hair, libido, penis growth, etc.) When I first when on HRT I was suppressed in a matter of weeks.


This is not nandrolone as in Deca. Its a methylated nortest that exibits sufficient andogenicity to support libido and other secondary sex characteristics but it will not support sperm formation, something that requires T, nor does it promote prostate growth. So with MENT, you get a one-two punch of inhibiting LH and no androgen support for sperm production, ergo better/more consistent sterility.
nightop
This approach is retarded and I love the irony of the AMA/FDA/Media/Public making AAS out to be so evil and then turning around and looking at this as a great new potential drug.
Proton Soup
QUOTE (Benson @ Apr 14 2008, 08:23 AM) *
Conversion to estrogen and DHT is an issue for some men with exogenous T even at HRT level doses.



This is not nandrolone as in Deca. Its a methylated nortest that exibits sufficient andogenicity to support libido and other secondary sex characteristics but it will not support sperm formation, something that requires T, nor does it promote prostate growth. So with MENT, you get a one-two punch of inhibiting LH and no androgen support for sperm production, ergo better/more consistent sterility.


if docs don't seem to care about birth control destroying women's libido, i doubt they'll care much about men's either.

have they done long-term studies?
D-termine
F this.
200wannabe
I have used Ment up to 50mg/day for four weeks (20,30,40,50), libido was fine, elevated if anything. No bloodwork unfortunatley. Nice compound, very lean gains, zero sides.
Sub7
Why does the pharmaceutical industry make androgen derivatives as male contraceptives?
Isn't spermatogenesis a separate process which is triggered by Testosterone but distinct from Testosterone production? Isn't it easier and much more sensible to target and stop one of intermediate steps in spermatogenesis instead of messing up the entire testosterone/libido/mental well being/etc.../etc... dimension ?
Benson
QUOTE (Sub7 @ Apr 16 2008, 12:25 AM) *
Why does the pharmaceutical industry make androgen derivatives as male contraceptives?
Isn't spermatogenesis a separate process which is triggered by Testosterone but distinct from Testosterone production? Isn't it easier and much more sensible to target and stop one of intermediate steps in spermatogenesis instead of messing up the entire testosterone/libido/mental well being/etc.../etc... dimension ?


The male reproductive system is fairly simple and robust. A successful contraceptive is something that can induce consistent and reversible sterility without producing deformed sperm and inducing LH/FSH shutdown is the simplest way to do this. There are some other drugs like adjudin that are non-hormonal but they are a long way off yet.


About the only downside I can see for MENT is that it will cause testicular atrophy which may be an issue in a culture that attaches importance to testicle size.
Proton Soup
just pick your size, anything from chihuahua to rottweiler. http://www.neuticles.com/sizing.php
Tkarrde
Neuticles kill me
Benson
QUOTE (Tkarrde @ Apr 17 2008, 07:52 PM) *
Neuticles kill me


I wanted to get them for my dog but the wife put her foot down...
doom3q
QUOTE (Mitosis @ Apr 14 2008, 09:49 AM) *
I was under the impression...though it may cause extremely low levels of sperm, that test does not cause consistent results with controlling pregnancy.

I heard about another drug that was working specifically on the sperm themselves....not working on the testes/HPTA. I do not know the details ....I dont remember....



And you're correct. It was only when combined with a progestin that it reduced sperm count enough.
Mitosis
QUOTE (doom3q @ Apr 17 2008, 05:34 PM) *
And you're correct. It was only when combined with a progestin that it reduced sperm count enough.



Good looking out.....

Sounds like a recipe for low sperm....


and for gyno haha.
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