Hi,

I don't like the "testicular entropy" (saw that in a post on one of the boards) that accompanies a cycle of reasonable length but I also don't like poking myself. I've never used HCG before but am considering it at a low dose during the cycle (not after) to keep the boys plump.

My questions are...

Is the HCG molecule small enough for TD application?

Will the TD medium degrade the HCG to the point where it will be ineffective?

I'm assuming that I'll have to reconstitute the HCG & mix it up every few days - correct? (I am clueless...Please remember I've never used it before).

Does anyone have any thoughts / suggestions?

Thanks for your time...

I couldn't find the molecular weight of HCG, so I don't know. HCG can be pricey, and I would think you are taking a chance if not injecting it, versuses potentially being able to be absorbed transdermally. HCG can be injected with an insulin pin subcutanousely, so the pain should be minimal.

Holy shnikies - I think its MW is 36,700.

( http://www.hcglab.com/synthesis.htm )


Inject it I will, mmmhhh!


Oh well - thanks anyway Pogue. (Are you Irish by the way or just a fan of the group?)

Looks like this question has already been answered but the correct answer would be NO. However speaking from experience 6-OXO works just as well if not better then HCG so if you really don't like injections I'd go that route. Cheers.

I would dare say that 6-OXO does work, but not the way HCG does. For the injecting part, it can either be done sub-Q or IM with a 29g needle, you barely feel anything.

Heathen, it is a pretty bold thing to say that 6-oxo works as well if not better than HCG.

Is this just based off experience, anaecdotal reports from others or what??

Im sorry but no way in hell will you get immeadate LH stimulation off of 6-OXO like you will HCG.

Thanks for the replies guys.

I'm not too concerned with the pain (my first two cycles were with old style chinese cyp..23g pin. The poke wasn't too bad but the pain afterwards was pretty bad). The whole injection process still wigs me out a bit though.

Any tips on storing it if I'm only going to use 500 iu a day?

Thanks again...

Once you mix the water with the powder, you need the refrigerate the leftover.

Thanks Pogue ....At what temperature should I keep my fridge? j/k

Actually I wasn't thinking of LH when I made my remarks of HCG vs. 6-OXO. What I was compairing was the responce that I have seen in the size of my nuts. For me 6-OXO worked much better then HCG works for me personally. Again this is just based on personal experience.

Actually if I was shooting for the best test recovery (based on my experience for me) I'd probably combine femara 2.5mg ED with 100mg of clomid ED. Then if I was having libido problems I might add some HCG but personally I have never responded that well to HCG.

My last thoughts on the subject have to do with availability. I live in a country where I can import (and I have some good sources) plus my Doctor is fairly loose with her scripts and she have never turned me down when I asked for something but those of you that live in the states might have a harder time getting HGC, clomid, arimadex and femara SO I thought that 6-OXO because it's legal and easy to get would be the next best thing. Cheers.

Thanks for the info Heathen. I'll have to read a bit more about 6-OXO.

There are probably around a dozen or so good threads about it in the general supplement section. Pat posts on this board so there are also a lot of his coments too. Cheers.

Is it true that reconstituted HCG is only good for about 30 days?

Yes, package lit says to discard after 30 days. My Doc uses his for 6 weeks so, I've been doing the same.
But, I'm not sure if the 30 day timeframe is relative to diminishing potency or the possibility of microbial buildup due to the low percentage of BA.

I would recommend against the use of HCG until you notice testicular atrophy starting to occur. The reason I say this is that your recovery will be hampered if your testicles are desensitized to leutinizing hormone. For myself, I have been on long long cycles with little or no testicular atrophy until the 4-5 month point, at which point a mild dose of HCG (500iu) boosts them up for another few months. I wouldn't use HCG unless you're going on longer than 4 months, its not worth the potential for recovery issues.

Transdermal is unlikely to be an option, sublingual is an option - but with a conversion rate of 8% to 13% it won't be a cheap method...

Just put the hCG in a slin pin and "man up"... Little and often is better than mega dosing at female fertility treatment levels...

30 days *should* be ok with the solvent, but if you have the money get bac water instead just to make sure... Or get the 1000IU/1500iu amps as opposed to the 5000IU amps...

Does using bac water extend the shelf life?

Yes is the short answer. The powder is good for goodness knows how long, and the solvent - assuming you have a pharma source - is good for 30days, but bac water should give you that bit longer...

Thats assuming you are keeping it in the slin pins once mixed....?

What if the reconstituted solution was transfered to a sealed vial?

*Should* be ok for a month to 6 weeks, although I don't see a reason as to why it would be kept longer than about 40days (Assuming a 5000iu amp, and a protocol of 250iu EOD)

Novarel brand hcg says to disgard after 30 days while Abraxis (APP) says 60. Don't know why.

In powdered form or once mixed...?

I had it confirmed with Organon the other day - their solvent is 0.9% sodium chloride in distilled water ... Other brands may vary...